Basic Information
ID: ALA3882742
Type: Binding
Description: Inhibition of recombinant human CDS1 using N-terminal biotin-labeled SGLYRSPSMPENLNRPR as substrate in presence of [gamma-33P]-adenosine triphosphate after 3 hrs by scintillation counting method
Format: BAO_0000357
Organism: Homo sapiens
Target: Serine/threonine-protein kinase Chk2(ALA2527)
Document: ALA3882722
Inhibition of recombinant human CDS1 using N-terminal biotin-labeled SGLYRSPSMPENLNRPR as substrate in presence of [gamma-33P]-adenosine triphosphate after 3 hrs by scintillation counting method: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3882742
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 446.53 | 3.68 | 3.68 |
| 349.43 | 3.94 | 3.94 |
| 419.82 | 3.94 | 3.94 |
| 420.49 | 3.12 | 3.12 |
| 341.37 | 3.56 | 3.56 |
| 342.36 | 2.95 | 2.95 |
| 394.43 | 3.96 | 3.96 |
| 344.37 | 2.81 | 2.81 |
| 355.44 | 4.48 | 4.48 |
| 342.40 | 4.10 | 4.10 |
| 432.51 | 3.29 | 3.29 |
| 355.44 | 4.54 | 4.54 |
| 347.40 | 3.62 | 3.62 |
| 357.41 | 3.72 | 3.72 |
| 392.42 | 4.11 | 4.11 |
| 391.43 | 4.71 | 4.71 |
| 405.84 | 4.30 | 4.30 |
| 418.48 | 3.03 | 3.03 |
| 375.82 | 4.21 | 4.21 |
| 440.91 | 3.46 | 3.46 |
| 355.40 | 3.87 | 3.87 |
| 475.36 | 4.11 | 4.11 |
| 371.40 | 3.57 | 3.57 |
| 371.44 | 4.03 | 4.03 |
| 371.44 | 3.97 | 3.97 |
| 396.43 | 2.40 | 2.40 |
| 412.50 | 2.87 | 2.87 |
| 443.81 | 5.23 | 5.23 |
| 419.87 | 4.23 | 4.23 |
| 375.86 | 5.13 | 5.13 |
| 357.41 | 3.93 | 3.93 |
| 377.83 | 4.06 | 4.06 |
| 412.28 | 4.72 | 4.72 |
| 393.45 | 4.56 | 4.56 |
| 341.41 | 4.23 | 4.23 |
| 385.42 | 3.69 | 3.69 |
| 445.83 | 5.08 | 5.08 |
| 387.40 | 3.14 | 3.14 |
| 369.42 | 4.18 | 4.18 |
| 410.26 | 4.87 | 4.87 |
| 418.48 | 3.08 | 3.08 |
| 375.82 | 4.21 | 4.21 |
| 377.83 | 4.06 | 4.06 |
| 347.42 | 4.09 | 4.09 |
| 377.45 | 5.07 | 5.07 |
| 373.41 | 3.42 | 3.42 |
| 355.40 | 3.87 | 3.87 |
| 361.83 | 4.57 | 4.57 |
| 436.49 | 2.82 | 2.82 |
| 371.40 | 3.57 | 3.57 |
| 333.44 | 4.45 | 4.45 |
| 420.49 | 3.15 | 3.15 |
| 349.42 | 3.47 | 3.47 |
| 399.41 | 3.33 | 3.33 |
| 349.39 | 2.94 | 2.94 |
| 351.41 | 2.79 | 2.79 |
| 385.38 | 3.29 | 3.29 |
| 407.46 | 2.20 | 2.20 |
| 445.95 | 3.98 | 3.98 |
| 480.32 | 4.34 | 4.34 |
| 406.47 | 2.81 | 2.81 |
| 385.42 | 3.58 | 3.58 |
| 373.41 | 3.42 | 3.42 |
| 447.97 | 4.22 | 4.22 |
| 410.26 | 4.87 | 4.87 |
| 357.41 | 3.72 | 3.72 |
| 412.28 | 4.72 | 4.72 |
| 420.49 | 3.12 | 3.12 |
| 421.84 | 3.79 | 3.79 |
| 369.42 | 4.12 | 4.12 |
| 420.49 | 3.37 | 3.37 |
| 373.84 | 5.04 | 5.04 |
| 401.42 | 3.18 | 3.18 |
| 343.39 | 3.41 | 3.41 |
| 420.49 | 3.12 | 3.12 |
| 411.87 | 3.76 | 3.76 |
| 357.41 | 4.06 | 4.06 |
| 482.33 | 4.19 | 4.19 |