Basic Information
ID: ALA3882746
Type: Binding
Description: Inhibition of human C17,20-lyase in human testis microsomes at 10 nM using 17alpha-hydroxypregnenolone/[21-3H]-17alpha-hydroxypregnenolone as substrate after 30 mins by scintillation counting method relative to control
Organism: Homo sapiens
Tissue: Testis
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3882746
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 374.53 | 5.03 | 5.03 |
| 394.56 | 4.48 | 4.48 |
| 408.63 | 6.34 | 6.34 |
| 350.51 | 5.26 | 5.26 |
| 393.62 | 7.30 | 7.30 |
| 363.59 | 7.21 | 7.21 |
| 389.54 | 5.89 | 5.89 |
| 350.51 | 5.26 | 5.26 |
| 353.51 | 4.10 | 4.10 |
| 345.49 | 5.53 | 5.53 |
| 378.56 | 5.39 | 5.39 |
| 353.51 | 4.10 | 4.10 |
| 379.54 | 5.58 | 5.58 |
| 390.57 | 5.73 | 5.73 |
| 347.50 | 5.61 | 5.61 |
| 392.59 | 5.59 | 5.59 |
| 365.52 | 5.27 | 5.27 |
| 380.53 | 4.17 | 4.17 |
| 326.48 | 4.35 | 4.35 |
| 420.64 | 6.37 | 6.37 |
| 353.51 | 4.11 | 4.11 |
| 422.61 | 5.87 | 5.87 |
| 382.55 | 5.31 | 5.31 |
| 338.54 | 6.16 | 6.16 |
| 378.56 | 5.23 | 5.23 |
| 362.52 | 4.86 | 4.86 |
| 406.57 | 5.11 | 5.11 |
| 350.55 | 5.56 | 5.56 |
| 383.54 | 4.70 | 4.70 |
| 375.51 | 5.54 | 5.54 |
| 338.50 | 4.95 | 4.95 |
| 340.51 | 4.74 | 4.74 |
| 363.59 | 7.21 | 7.21 |
| 352.48 | 3.42 | 3.42 |
| 379.59 | 6.91 | 6.91 |
| 362.56 | 5.58 | 5.58 |
| 390.53 | 4.69 | 4.69 |
| 420.60 | 5.55 | 5.55 |
| 390.57 | 5.33 | 5.33 |
| 362.52 | 5.39 | 5.39 |
| 415.58 | 5.52 | 5.52 |
| 362.52 | 4.76 | 4.76 |
| 376.54 | 5.11 | 5.11 |
| 365.52 | 4.33 | 4.33 |
| 351.53 | 5.74 | 5.74 |
| 362.52 | 4.76 | 4.76 |
| 336.48 | 4.87 | 4.87 |
| 377.62 | 7.46 | 7.46 |
| 353.47 | 2.81 | 2.81 |
| 360.50 | 4.68 | 4.68 |
| 363.55 | 6.00 | 6.00 |
| 365.56 | 6.05 | 6.05 |
| 347.50 | 5.32 | 5.32 |
| 362.52 | 4.76 | 4.76 |
| 390.57 | 5.41 | 5.41 |
| 419.57 | 5.90 | 5.90 |
| 365.56 | 6.05 | 6.05 |
| 378.60 | 6.12 | 6.12 |
| 325.46 | 3.95 | 3.95 |
| 352.48 | 3.42 | 3.42 |
| 338.50 | 4.66 | 4.66 |
| 376.54 | 5.07 | 5.07 |
| 380.58 | 5.56 | 5.56 |
| 334.46 | 4.79 | 4.79 |
| 340.51 | 3.97 | 3.97 |
| 365.56 | 5.79 | 5.79 |
| 340.51 | 3.97 | 3.97 |
| 361.57 | 6.99 | 6.99 |
| 404.60 | 5.67 | 5.67 |
| 365.52 | 4.37 | 4.37 |
| 349.48 | 3.94 | 3.94 |
| 394.56 | 5.09 | 5.09 |
| 380.53 | 5.23 | 5.23 |
| 324.47 | 4.56 | 4.56 |
| 391.56 | 5.97 | 5.97 |
| 364.58 | 5.86 | 5.86 |
| 349.52 | 5.69 | 5.69 |
| 362.52 | 4.86 | 4.86 |
| 434.62 | 5.89 | 5.89 |
| 363.55 | 6.44 | 6.44 |
| 349.52 | 5.40 | 5.40 |
| 384.01 | 7.55 | 7.55 |
| 409.57 | 5.67 | 5.67 |
| 333.52 | 6.43 | 6.43 |
| 392.59 | 5.64 | 5.64 |
| 351.49 | 4.02 | 4.02 |
| 339.48 | 4.05 | 4.05 |
| 363.50 | 4.29 | 4.29 |
| 395.59 | 6.14 | 6.14 |
| 381.56 | 5.75 | 5.75 |
| 395.54 | 5.28 | 5.28 |
| 388.56 | 5.33 | 5.33 |
| 351.54 | 4.84 | 4.84 |
| 352.48 | 3.42 | 3.42 |
| 392.54 | 4.77 | 4.77 |
| 390.62 | 6.14 | 6.14 |
| 395.59 | 6.14 | 6.14 |
| 401.55 | 5.18 | 5.18 |
| 354.50 | 3.50 | 3.50 |
| 363.51 | 4.16 | 4.16 |
| 352.48 | 3.42 | 3.42 |
| 327.47 | 3.74 | 3.74 |
| 382.55 | 4.23 | 4.23 |
| 355.49 | 2.90 | 2.90 |
| 365.52 | 5.27 | 5.27 |
| 364.53 | 5.08 | 5.08 |
| 424.59 | 4.57 | 4.57 |
| 378.52 | 5.15 | 5.15 |
| 404.55 | 5.03 | 5.03 |
| 349.56 | 6.90 | 6.90 |
| 379.54 | 5.70 | 5.70 |
| 363.51 | 4.16 | 4.16 |
| 354.50 | 3.50 | 3.50 |
| 376.59 | 6.24 | 6.24 |
| 394.56 | 4.86 | 4.86 |
| 347.55 | 6.74 | 6.74 |
| 351.53 | 5.74 | 5.74 |
| 377.53 | 5.33 | 5.33 |
| 381.56 | 5.75 | 5.75 |