Basic Information
ID: ALA3882747
Type: Binding
Description: Inhibition of CYP17 in human H295R cells assessed as decrease in testosterone levels after 24 hrs by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: H295R
Target: Cytochrome P450 17A1(ALA3522)
Document: ALA3882724
Inhibition of CYP17 in human H295R cells assessed as decrease in testosterone levels after 24 hrs by ELISA: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3882747
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.52 | 5.40 | 5.40 |
| 374.53 | 5.03 | 5.03 |
| 337.47 | 3.93 | 3.93 |
| 363.59 | 7.21 | 7.21 |
| 392.52 | 5.07 | 5.07 |
| 381.54 | 5.93 | 5.93 |
| 442.63 | 4.77 | 4.77 |
| 353.51 | 4.10 | 4.10 |
| 479.66 | 7.80 | 7.80 |
| 375.52 | 4.42 | 4.42 |
| 378.49 | 4.82 | 4.82 |
| 361.53 | 5.63 | 5.63 |
| 446.64 | 6.85 | 6.85 |
| 392.59 | 5.59 | 5.59 |
| 446.64 | 5.94 | 5.94 |
| 393.55 | 6.38 | 6.38 |
| 326.48 | 4.35 | 4.35 |
| 390.57 | 5.54 | 5.54 |
| 363.55 | 5.79 | 5.79 |
| 357.50 | 5.55 | 5.55 |
| 422.61 | 5.87 | 5.87 |
| 382.55 | 5.31 | 5.31 |
| 378.56 | 5.23 | 5.23 |
| 380.51 | 5.20 | 5.20 |
| 377.57 | 6.36 | 6.36 |
| 363.55 | 5.48 | 5.48 |
| 390.57 | 5.33 | 5.33 |
| 361.49 | 5.27 | 5.27 |
| 359.51 | 5.46 | 5.46 |
| 351.53 | 5.48 | 5.48 |
| 390.57 | 5.33 | 5.33 |
| 410.61 | 5.06 | 5.06 |
| 409.52 | 6.57 | 6.57 |
| 378.56 | 5.10 | 5.10 |
| 465.64 | 7.49 | 7.49 |
| 403.57 | 6.28 | 6.28 |
| 362.52 | 4.76 | 4.76 |
| 385.52 | 4.54 | 4.54 |
| 367.51 | 5.54 | 5.54 |
| 363.48 | 5.67 | 5.67 |
| 365.56 | 5.72 | 5.72 |
| 390.57 | 5.41 | 5.41 |
| 435.66 | 6.05 | 6.05 |
| 325.46 | 3.95 | 3.95 |
| 379.93 | 6.18 | 6.18 |
| 376.54 | 5.07 | 5.07 |
| 414.54 | 5.78 | 5.78 |
| 379.55 | 4.80 | 4.80 |
| 425.56 | 7.18 | 7.18 |
| 363.50 | 4.53 | 4.53 |
| 379.48 | 4.92 | 4.92 |
| 379.59 | 6.11 | 6.11 |
| 336.48 | 4.58 | 4.58 |
| 337.51 | 5.09 | 5.09 |
| 349.48 | 3.94 | 3.94 |
| 376.54 | 5.45 | 5.45 |
| 394.56 | 5.09 | 5.09 |
| 376.54 | 4.99 | 4.99 |
| 479.66 | 7.80 | 7.80 |
| 369.50 | 6.51 | 6.51 |
| 388.56 | 5.46 | 5.46 |
| 391.56 | 5.97 | 5.97 |
| 349.52 | 5.69 | 5.69 |
| 387.57 | 6.24 | 6.24 |
| 434.62 | 5.89 | 5.89 |
| 430.64 | 6.32 | 6.32 |
| 363.55 | 6.44 | 6.44 |
| 410.51 | 5.62 | 5.62 |
| 349.52 | 5.40 | 5.40 |
| 399.55 | 4.98 | 4.98 |
| 377.57 | 6.03 | 6.03 |
| 351.49 | 4.02 | 4.02 |
| 359.51 | 5.77 | 5.77 |
| 357.50 | 5.55 | 5.55 |
| 381.56 | 5.75 | 5.75 |
| 442.63 | 4.12 | 4.12 |
| 353.55 | 5.57 | 5.57 |
| 415.60 | 4.17 | 4.17 |
| 416.61 | 5.93 | 5.93 |
| 395.59 | 6.14 | 6.14 |
| 350.55 | 5.44 | 5.44 |
| 392.52 | 4.76 | 4.76 |
| 458.57 | 6.56 | 6.56 |
| 379.52 | 6.05 | 6.05 |
| 327.47 | 3.74 | 3.74 |
| 363.55 | 5.71 | 5.71 |
| 380.51 | 5.82 | 5.82 |
| 424.59 | 4.57 | 4.57 |
| 359.51 | 5.77 | 5.77 |
| 363.51 | 4.16 | 4.16 |
| 414.55 | 5.05 | 5.05 |
| 363.55 | 5.79 | 5.79 |
| 403.51 | 4.68 | 4.68 |
| 423.60 | 7.00 | 7.00 |
| 392.59 | 5.62 | 5.62 |
| 362.52 | 4.98 | 4.98 |
| 374.53 | 5.27 | 5.27 |
| 422.61 | 5.63 | 5.63 |
| 375.56 | 5.95 | 5.95 |
| 369.55 | 4.81 | 4.81 |