Basic Information
ID: ALA3882749
Type: ADME
Description: Half life in human liver microsomes at 1 uM by LC-MS/MS analysis
Format: BAO_0000221
Organism: Homo sapiens
Tissue: Liver
Target: Liver(ALA613419)
Document: ALA3882724
Half life in human liver microsomes at 1 uM by LC-MS/MS analysis: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3882749
t1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 374.53 | 5.03 | 5.03 |
| 408.63 | 6.34 | 6.34 |
| 393.62 | 7.30 | 7.30 |
| 406.55 | 5.41 | 5.41 |
| 403.57 | 5.11 | 5.11 |
| 441.59 | 7.14 | 7.14 |
| 378.56 | 5.39 | 5.39 |
| 452.66 | 5.49 | 5.49 |
| 348.49 | 4.67 | 4.67 |
| 373.54 | 6.00 | 6.00 |
| 380.53 | 4.17 | 4.17 |
| 390.57 | 5.54 | 5.54 |
| 420.64 | 6.27 | 6.27 |
| 338.54 | 6.16 | 6.16 |
| 363.55 | 6.05 | 6.05 |
| 414.55 | 5.05 | 5.05 |
| 405.59 | 5.19 | 5.19 |
| 364.53 | 4.98 | 4.98 |
| 390.57 | 5.33 | 5.33 |
| 392.52 | 5.07 | 5.07 |
| 361.49 | 5.27 | 5.27 |
| 359.51 | 5.46 | 5.46 |
| 420.60 | 5.55 | 5.55 |
| 390.57 | 5.33 | 5.33 |
| 424.54 | 5.87 | 5.87 |
| 362.52 | 4.76 | 4.76 |
| 379.59 | 6.26 | 6.26 |
| 507.72 | 8.48 | 8.48 |
| 365.49 | 5.46 | 5.46 |
| 363.55 | 5.94 | 5.94 |
| 367.51 | 5.54 | 5.54 |
| 409.61 | 5.62 | 5.62 |
| 377.62 | 7.46 | 7.46 |
| 385.52 | 4.54 | 4.54 |
| 363.55 | 5.89 | 5.89 |
| 400.01 | 6.52 | 6.52 |
| 365.56 | 6.05 | 6.05 |
| 347.50 | 5.32 | 5.32 |
| 362.52 | 4.76 | 4.76 |
| 391.60 | 6.26 | 6.26 |
| 367.51 | 5.54 | 5.54 |
| 363.48 | 5.67 | 5.67 |
| 365.56 | 5.72 | 5.72 |
| 385.55 | 6.16 | 6.16 |
| 418.63 | 6.01 | 6.01 |
| 397.51 | 6.26 | 6.26 |
| 378.56 | 5.15 | 5.15 |
| 365.56 | 6.05 | 6.05 |
| 378.60 | 6.12 | 6.12 |
| 409.62 | 5.62 | 5.62 |
| 379.93 | 6.18 | 6.18 |
| 389.51 | 6.89 | 6.89 |
| 412.52 | 5.70 | 5.70 |
| 379.55 | 4.80 | 4.80 |
| 449.64 | 5.73 | 5.73 |
| 357.50 | 5.69 | 5.69 |
| 376.54 | 4.99 | 4.99 |
| 415.57 | 6.66 | 6.66 |
| 419.61 | 6.53 | 6.53 |
| 369.50 | 6.51 | 6.51 |
| 381.54 | 5.85 | 5.85 |
| 388.56 | 5.46 | 5.46 |
| 391.56 | 5.97 | 5.97 |
| 329.49 | 6.12 | 6.12 |
| 349.52 | 5.69 | 5.69 |
| 363.55 | 5.79 | 5.79 |
| 472.67 | 6.21 | 6.21 |
| 363.55 | 6.44 | 6.44 |
| 390.57 | 5.33 | 5.33 |
| 410.51 | 5.62 | 5.62 |
| 392.59 | 5.41 | 5.41 |
| 399.55 | 4.98 | 4.98 |
| 392.59 | 5.64 | 5.64 |
| 351.49 | 4.02 | 4.02 |
| 359.51 | 5.77 | 5.77 |
| 363.50 | 4.29 | 4.29 |
| 355.53 | 4.79 | 4.79 |
| 363.48 | 5.67 | 5.67 |
| 406.61 | 5.96 | 5.96 |
| 435.68 | 5.89 | 5.89 |
| 380.51 | 5.20 | 5.20 |
| 347.50 | 5.01 | 5.01 |
| 369.50 | 6.67 | 6.67 |
| 354.50 | 3.50 | 3.50 |
| 360.50 | 5.11 | 5.11 |
| 379.52 | 6.05 | 6.05 |
| 380.51 | 5.82 | 5.82 |
| 375.56 | 5.48 | 5.48 |
| 379.52 | 5.99 | 5.99 |
| 376.54 | 6.11 | 6.11 |
| 424.59 | 4.57 | 4.57 |
| 349.56 | 6.90 | 6.90 |
| 363.55 | 5.79 | 5.79 |
| 389.51 | 6.06 | 6.06 |
| 365.56 | 5.87 | 5.87 |
| 374.53 | 5.27 | 5.27 |
| 376.54 | 5.07 | 5.07 |
| 361.53 | 5.72 | 5.72 |
| 369.55 | 4.81 | 4.81 |
| 451.61 | 7.18 | 7.18 |