Basic Information
ID: ALA3882754
Type: Binding
Description: Inhibition of His6-tagged JNK2 (unknown origin) assessed as reduction in c-Jun phosphorylation using GST-c-Jun (1 to 79 residues) and [gamma32P]ATP incubated for 1 hr by scintillation counting assay
Format: BAO_0000357
Organism: Homo sapiens
Target: c-Jun N-terminal kinase 2(ALA4179)
Document: ALA3882725
Inhibition of His6-tagged JNK2 (unknown origin) assessed as reduction in c-Jun phosphorylation using GST-c-Jun (1 to 79 residues) and [gamma32P]ATP incubated for 1 hr by scintillation counting assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3882754
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 239.23 | 3.14 | 3.14 |
| 283.31 | 3.07 | 3.07 |
| 387.40 | 4.19 | 4.19 |
| 210.24 | 2.94 | 2.94 |
| 278.29 | 3.76 | 3.76 |
| 209.25 | 2.81 | 2.81 |
| 340.36 | 2.36 | 2.36 |
| 361.38 | 4.63 | 4.63 |
| 318.36 | 4.38 | 4.38 |
| 347.35 | 4.33 | 4.33 |
| 345.38 | 4.93 | 4.93 |
| 328.35 | 4.91 | 4.91 |
| 269.28 | 2.73 | 2.73 |
| 324.36 | 2.41 | 2.41 |
| 275.74 | 2.82 | 2.82 |
| 284.29 | 3.55 | 3.55 |
| 337.36 | 3.08 | 3.08 |
| 389.39 | 4.25 | 4.25 |
| 326.38 | 2.66 | 2.66 |
| 277.25 | 3.83 | 3.83 |
| 370.38 | 3.54 | 3.54 |
| 332.34 | 4.02 | 4.02 |
| 346.37 | 3.69 | 3.69 |
| 374.38 | 3.72 | 3.72 |
| 389.39 | 4.41 | 4.41 |
| 321.36 | 4.28 | 4.28 |
| 367.40 | 4.17 | 4.17 |
| 309.34 | 3.61 | 3.61 |
| 331.35 | 4.62 | 4.62 |
| 262.23 | 4.25 | 4.25 |
| 346.37 | 3.69 | 3.69 |
| 332.34 | 4.02 | 4.02 |
| 337.38 | 4.68 | 4.68 |
| 341.34 | 2.96 | 2.96 |
| 271.25 | 2.49 | 2.49 |
| 357.37 | 4.18 | 4.18 |
| 346.37 | 3.69 | 3.69 |
| 375.36 | 4.32 | 4.32 |
| 329.36 | 4.19 | 4.19 |
| 382.44 | 2.82 | 2.82 |
| 364.36 | 5.15 | 5.15 |
| 293.31 | 3.46 | 3.46 |
| 314.35 | 3.88 | 3.88 |
| 383.42 | 3.83 | 3.83 |
| 369.40 | 3.44 | 3.44 |
| 295.32 | 3.72 | 3.72 |
| 323.29 | 2.13 | 2.13 |
| 332.34 | 4.02 | 4.02 |
| 347.35 | 4.33 | 4.33 |
| 388.40 | 3.98 | 3.98 |
| 331.35 | 4.62 | 4.62 |
| 280.27 | 2.55 | 2.55 |
| 328.38 | 4.06 | 4.06 |
| 289.29 | 4.29 | 4.29 |
| 283.29 | 3.54 | 3.54 |
| 212.23 | 3.37 | 3.37 |
| 321.31 | 4.21 | 4.21 |
| 389.39 | 4.00 | 4.00 |
| 318.36 | 4.38 | 4.38 |
| 355.37 | 3.35 | 3.35 |
| 255.25 | 2.47 | 2.47 |
| 251.29 | 3.19 | 3.19 |
| 340.36 | 3.23 | 3.23 |
| 361.38 | 4.23 | 4.23 |
| 326.33 | 1.97 | 1.97 |
| 367.38 | 3.31 | 3.31 |
| 300.36 | 4.81 | 4.81 |
| 313.33 | 2.48 | 2.48 |
| 270.27 | 1.97 | 1.97 |
| 375.36 | 4.32 | 4.32 |
| 255.30 | 3.80 | 3.80 |
| 299.29 | 3.16 | 3.16 |
| 307.23 | 4.16 | 4.16 |
| 376.35 | 4.53 | 4.53 |
| 332.34 | 4.02 | 4.02 |
| 363.40 | 3.08 | 3.08 |
| 395.43 | 3.78 | 3.78 |
| 389.39 | 4.41 | 4.41 |
| 367.42 | 3.65 | 3.65 |
| 375.36 | 4.32 | 4.32 |
| 327.32 | 2.57 | 2.57 |
| 332.34 | 4.02 | 4.02 |
| 229.19 | 2.73 | 2.73 |
| 389.39 | 4.41 | 4.41 |
| 227.24 | 2.95 | 2.95 |
| 208.26 | 3.54 | 3.54 |
| 358.36 | 3.58 | 3.58 |
| 313.36 | 4.48 | 4.48 |
| 313.29 | 2.18 | 2.18 |
| 289.29 | 4.29 | 4.29 |
| 332.34 | 4.02 | 4.02 |
| 278.29 | 3.76 | 3.76 |
| 269.26 | 3.15 | 3.15 |
| 298.32 | 2.06 | 2.06 |
| 346.37 | 4.20 | 4.20 |
| 279.28 | 3.15 | 3.15 |
| 328.38 | 4.06 | 4.06 |
| 374.38 | 3.72 | 3.72 |
| 256.24 | 3.07 | 3.07 |
| 312.35 | 2.45 | 2.45 |