Basic Information
ID: ALA3882756
Type: Binding
Description: Inhibition of human IGF1R kinase domain (M954 to C1367 residues) tri-phosphorylated enzyme form expressed in baculovirus based expression system using poly-EY peptide incubated for 2 hrs by luciferase-luciferin coupled chemiluminescent assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Insulin-like growth factor I receptor(ALA1957)
Document: ALA3882726
Inhibition of human IGF1R kinase domain (M954 to C1367 residues) tri-phosphorylated enzyme form expressed in baculovirus based expression system using poly-EY peptide incubated for 2 hrs by luciferase-luciferin coupled chemiluminescent assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3882756
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 415.30 | 4.20 | 4.20 |
| 411.31 | 4.68 | 4.68 |
| 485.60 | 4.21 | 4.21 |
| 541.50 | 4.72 | 4.72 |
| 474.61 | 4.10 | 4.10 |
| 426.32 | 4.56 | 4.56 |
| 490.61 | 3.25 | 3.25 |
| 431.29 | 3.86 | 3.86 |
| 425.33 | 5.07 | 5.07 |
| 456.35 | 4.16 | 4.16 |
| 483.37 | 3.42 | 3.42 |
| 498.64 | 5.10 | 5.10 |
| 527.47 | 4.33 | 4.33 |
| 455.11 | 3.95 | 3.95 |
| 482.34 | 4.55 | 4.55 |
| 464.17 | 5.40 | 5.40 |
| 462.74 | 4.94 | 4.94 |
| 353.43 | 3.85 | 3.85 |
| 452.32 | 4.85 | 4.85 |
| 407.87 | 4.74 | 4.74 |
| 340.82 | 4.53 | 4.53 |
| 501.64 | 5.23 | 5.23 |
| 454.33 | 5.10 | 5.10 |
| 474.61 | 4.02 | 4.02 |
| 525.46 | 4.03 | 4.03 |
| 414.31 | 4.39 | 4.39 |
| 403.45 | 4.10 | 4.10 |
| 458.36 | 4.41 | 4.41 |
| 487.61 | 4.84 | 4.84 |
| 448.71 | 4.08 | 4.08 |
| 484.40 | 4.78 | 4.78 |
| 415.50 | 5.18 | 5.18 |
| 384.28 | 4.79 | 4.79 |
| 458.53 | 3.92 | 3.92 |
| 401.27 | 4.34 | 4.34 |
| 400.28 | 3.79 | 3.79 |
| 525.46 | 4.03 | 4.03 |
| 373.42 | 4.09 | 4.09 |
| 345.20 | 3.76 | 3.76 |
| 431.29 | 3.86 | 3.86 |
| 483.37 | 3.42 | 3.42 |
| 541.50 | 4.72 | 4.72 |
| 456.35 | 4.01 | 4.01 |
| 484.40 | 4.78 | 4.78 |
| 496.62 | 4.85 | 4.85 |
| 455.24 | 5.23 | 5.23 |
| 458.32 | 4.39 | 4.39 |
| 460.54 | 4.03 | 4.03 |
| 500.40 | 5.35 | 5.35 |
| 555.53 | 5.11 | 5.11 |
| 484.40 | 4.94 | 4.94 |
| 511.43 | 4.15 | 4.15 |
| 460.59 | 3.71 | 3.71 |
| 393.50 | 4.78 | 4.78 |
| 450.32 | 2.97 | 2.97 |
| 339.40 | 3.54 | 3.54 |
| 488.64 | 4.41 | 4.41 |
| 402.46 | 4.13 | 4.13 |
| 489.46 | 6.01 | 6.01 |
| 431.50 | 4.88 | 4.88 |
| 502.67 | 4.80 | 4.80 |
| 387.45 | 4.40 | 4.40 |
| 406.24 | 4.04 | 4.04 |
| 513.44 | 4.40 | 4.40 |
| 450.14 | 5.09 | 5.09 |
| 418.30 | 4.31 | 4.31 |
| 476.63 | 4.26 | 4.26 |
| 468.36 | 5.27 | 5.27 |
| 399.30 | 4.76 | 4.76 |
| 431.29 | 4.34 | 4.34 |
| 385.27 | 4.64 | 4.64 |
| 414.27 | 3.43 | 3.43 |
| 471.57 | 3.84 | 3.84 |
| 488.64 | 4.49 | 4.49 |
| 389.46 | 4.64 | 4.64 |
| 474.61 | 4.10 | 4.10 |
| 542.48 | 4.98 | 4.98 |
| 458.36 | 4.27 | 4.27 |
| 375.44 | 4.33 | 4.33 |
| 514.43 | 4.43 | 4.43 |
| 457.34 | 3.56 | 3.56 |
| 437.69 | 4.63 | 4.63 |
| 386.26 | 3.91 | 3.91 |
| 462.60 | 3.95 | 3.95 |
| 497.14 | 4.93 | 4.93 |
| 405.69 | 4.98 | 4.98 |
| 426.28 | 4.28 | 4.28 |
| 442.53 | 4.69 | 4.69 |
| 387.45 | 4.40 | 4.40 |
| 511.43 | 3.64 | 3.64 |
| 449.52 | 5.75 | 5.75 |
| 386.26 | 3.91 | 3.91 |
| 417.27 | 3.55 | 3.55 |
| 541.50 | 4.72 | 4.72 |
| 435.71 | 4.99 | 4.99 |
| 513.44 | 4.40 | 4.40 |
| 527.47 | 4.79 | 4.79 |
| 431.46 | 3.87 | 3.87 |
| 488.64 | 4.41 | 4.41 |
| 470.38 | 4.35 | 4.35 |