Cytotoxicity against human SV5A8 cells expressing SV40 binding sites driving firefly/renilla luciferase reporter gene after 24 hrs by luminometer

Basic Information

ID: ALA3883062

Type: ADME

Description: Cytotoxicity against human SV5A8 cells expressing SV40 binding sites driving firefly/renilla luciferase reporter gene after 24 hrs by luminometer

Format: BAO_0000219

Organism: Homo sapiens

Cell type: SV5A8

Target: NON-PROTEIN TARGET(ALA3879801)

Document: ALA3882728

Cytotoxicity against human SV5A8 cells expressing SV40 binding sites driving firefly/renilla luciferase reporter gene after 24 hrs by luminometer: 38

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3883062

IC50

Total(262)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
415.47	4.98	4.98
484.58	4.69	4.69
431.93	5.50	5.50
432.92	4.89	4.89
401.45	4.68	4.68
418.89	4.58	4.58
432.92	4.89	4.89
471.54	4.78	4.78
417.90	5.19	5.19
415.47	4.98	4.98
415.47	4.98	4.98
469.56	5.93	5.93
541.37	5.30	5.30
459.55	6.20	6.20
440.48	4.57	4.57
457.51	4.90	4.90
432.92	4.89	4.89
418.89	4.58	4.58
429.50	5.01	5.01
470.55	4.35	4.35
459.53	4.75	4.75
443.48	4.51	4.51
443.53	5.76	5.76
445.50	4.19	4.19
472.57	4.76	4.76
441.51	5.15	5.15
441.51	5.34	5.34
443.53	5.26	5.26
451.45	5.55	5.55
417.90	5.19	5.19
415.47	4.98	4.98
431.93	5.50	5.50
484.58	4.74	4.74
408.47	4.41	4.41
397.48	4.84	4.84
498.61	5.13	5.13
431.93	5.50	5.50
431.93	5.50	5.50
455.54	5.54	5.54
561.11	6.26	6.26
498.63	5.06	5.06
498.64	4.19	4.19
526.66	5.61	5.61
508.67	5.47	5.47
522.70	5.78	5.78
508.67	5.83	5.83
526.66	5.61	5.61
520.68	5.61	5.61
543.12	6.12	6.12
534.71	6.00	6.00
562.76	6.78	6.78
565.77	5.40	5.40
579.79	5.79	5.79
563.75	5.15	5.15
593.78	4.56	4.56
617.84	6.47	6.47
432.57	3.90	3.90
538.70	5.48	5.48
474.65	4.92	4.92
474.65	5.07	5.07
500.69	5.60	5.60
526.66	5.61	5.61
415.47	4.70	4.70
470.55	4.39	4.39
415.47	5.07	5.07
449.92	5.64	5.64
435.89	5.33	5.33
483.59	6.32	6.32
497.62	6.90	6.90
519.58	6.18	6.18
497.62	6.61	6.61
547.64	5.66	5.66
485.90	6.21	6.21
520.61	6.02	6.02
576.67	6.49	6.49
455.54	5.54	5.54
445.95	5.52	5.52
534.71	6.19	6.19
527.00	6.41	6.41
497.62	6.90	6.90
483.59	6.32	6.32
517.61	7.01	7.01
441.51	5.60	5.60
551.96	7.37	7.37
460.97	5.48	5.48
418.89	4.58	4.58
574.70	7.02	7.02
544.65	5.75	5.75
457.55	5.79	5.79
476.38	5.61	5.61
459.53	4.37	4.37
445.95	5.81	5.81
443.53	5.57	5.57
471.32	5.38	5.38
498.61	5.45	5.45
445.50	4.19	4.19
542.62	5.22	5.22
534.71	6.19	6.19
558.81	5.21	5.21
558.81	5.21	5.21
544.10	5.52	5.52
576.79	7.22	7.22
441.51	5.23	5.23
460.97	5.48	5.48
465.48	5.86	5.86
472.98	5.81	5.81
494.64	5.44	5.44
478.94	4.60	4.60
449.92	5.64	5.64
497.62	6.76	6.76
572.84	5.77	5.77
580.63	6.32	6.32
604.69	5.99	5.99
447.93	5.20	5.20
443.53	5.40	5.40
484.58	4.74	4.74
581.70	4.69	4.69
455.54	5.73	5.73
429.50	5.54	5.54
599.78	6.47	6.47
445.45	4.13	4.13
509.66	4.86	4.86
541.68	4.99	4.99
520.68	5.61	5.61
443.53	5.48	5.48
433.46	5.12	5.12
538.70	4.83	4.83
460.97	5.48	5.48
541.37	5.30	5.30
455.54	5.73	5.73
617.84	6.47	6.47
534.71	6.00	6.00
446.94	5.20	5.20
531.59	7.11	7.11
430.49	5.09	5.09
508.67	5.47	5.47
469.56	5.93	5.93
523.04	6.51	6.51
593.71	8.54	8.54
577.78	5.59	5.59
536.51	4.72	4.72
433.46	5.12	5.12
501.56	5.39	5.39
500.05	6.84	6.84
566.60	6.29	6.29
460.97	5.91	5.91
445.95	5.52	5.52
513.62	5.68	5.68
484.58	5.13	5.13
497.99	6.76	6.76
433.46	5.12	5.12
544.65	5.75	5.75
526.62	5.00	5.00
429.50	5.54	5.54
457.51	4.47	4.47
495.56	6.17	6.17
500.62	5.33	5.33
448.91	4.59	4.59
460.97	5.48	5.48
444.51	4.16	4.16
439.49	4.68	4.68
458.95	5.25	5.25
433.46	5.12	5.12
469.56	6.38	6.38
466.37	6.15	6.15
472.98	5.64	5.64
606.67	7.21	7.21
455.54	5.62	5.62
460.97	5.91	5.91
542.62	5.22	5.22
487.01	6.20	6.20
525.96	7.13	7.13
620.54	5.76	5.76
548.63	5.06	5.06
470.55	4.35	4.35
452.35	5.84	5.84
455.54	5.58	5.58
464.93	5.06	5.06
473.55	5.02	5.02
590.40	5.61	5.61
455.54	5.99	5.99
536.72	6.28	6.28
527.98	7.01	7.01
519.58	6.18	6.18
569.69	4.59	4.59
447.49	5.15	5.15
606.67	6.85	6.85
467.45	5.43	5.43
480.62	5.13	5.13
498.61	5.08	5.08
535.63	5.83	5.83
429.50	5.01	5.01
592.64	6.46	6.46
415.47	4.98	4.98
506.59	5.97	5.97
534.64	6.43	6.43
560.70	6.61	6.61
544.65	5.75	5.75
412.50	4.55	4.55
427.48	5.21	5.21
562.64	5.88	5.88
490.41	5.63	5.63
457.55	5.79	5.79
494.64	5.44	5.44
627.80	5.52	5.52
498.61	5.05	5.05
626.81	6.12	6.12
538.67	6.01	6.01
444.51	5.40	5.40
466.37	6.15	6.15
429.50	5.29	5.29
499.59	5.56	5.56
458.95	5.25	5.25
463.94	5.95	5.95
546.65	6.27	6.27
520.68	5.80	5.80
498.61	5.00	5.00
532.69	5.78	5.78
455.54	5.73	5.73
538.67	6.01	6.01
432.92	4.61	4.61
535.63	5.83	5.83
517.61	6.87	6.87
510.82	6.26	6.26
506.59	5.99	5.99
443.53	5.57	5.57
561.11	6.26	6.26
563.75	5.20	5.20
433.46	4.84	4.84
627.80	5.52	5.52
499.92	6.23	6.23
473.51	4.49	4.49
608.68	7.10	7.10
444.51	5.40	5.40
484.58	4.74	4.74
525.96	6.77	6.77
520.68	5.80	5.80
422.49	4.72	4.72
484.58	4.69	4.69
494.64	5.16	5.16
429.44	3.84	3.84
496.59	4.61	4.61
699.76	6.37	6.37
505.42	6.02	6.02
505.60	6.58	6.58
443.53	5.32	5.32
619.05	6.28	6.28
498.56	4.22	4.22
415.47	4.98	4.98
446.94	4.92	4.92
498.61	5.08	5.08
467.50	5.84	5.84
511.94	6.38	6.38
547.64	5.66	5.66
558.68	6.31	6.31
426.52	4.57	4.57
475.00	5.73	5.73
427.48	4.84	4.84
584.77	7.04	7.04
457.55	5.82	5.82
563.75	5.20	5.20
508.67	5.47	5.47