ID: ALA3883063
Type: Binding
Description: Inhibition of TCF-4/beta catenin in human Tcf33.13 cells expressing Tcf-4/SV40 binding sites driving firefly luciferase reporter gene after 24 hrs by luminometer
Organism: Homo sapiens
Cell type: Tcf33.13
Bioactivity
Activity Types for Assay ALA3883063
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
415.47 | 4.98 | 4.98 |
484.58 | 4.69 | 4.69 |
431.93 | 5.50 | 5.50 |
432.92 | 4.89 | 4.89 |
401.45 | 4.68 | 4.68 |
418.89 | 4.58 | 4.58 |
432.92 | 4.89 | 4.89 |
471.54 | 4.78 | 4.78 |
417.90 | 5.19 | 5.19 |
415.47 | 4.98 | 4.98 |
415.47 | 4.98 | 4.98 |
469.56 | 5.93 | 5.93 |
541.37 | 5.30 | 5.30 |
459.55 | 6.20 | 6.20 |
440.48 | 4.57 | 4.57 |
457.51 | 4.90 | 4.90 |
432.92 | 4.89 | 4.89 |
418.89 | 4.58 | 4.58 |
429.50 | 5.01 | 5.01 |
470.55 | 4.35 | 4.35 |
459.53 | 4.75 | 4.75 |
443.48 | 4.51 | 4.51 |
443.53 | 5.76 | 5.76 |
445.50 | 4.19 | 4.19 |
472.57 | 4.76 | 4.76 |
441.51 | 5.15 | 5.15 |
441.51 | 5.34 | 5.34 |
443.53 | 5.26 | 5.26 |
451.45 | 5.55 | 5.55 |
417.90 | 5.19 | 5.19 |
415.47 | 4.98 | 4.98 |
431.93 | 5.50 | 5.50 |
484.58 | 4.74 | 4.74 |
408.47 | 4.41 | 4.41 |
397.48 | 4.84 | 4.84 |
498.61 | 5.13 | 5.13 |
431.93 | 5.50 | 5.50 |
431.93 | 5.50 | 5.50 |
455.54 | 5.54 | 5.54 |
561.11 | 6.26 | 6.26 |
498.63 | 5.06 | 5.06 |
498.64 | 4.19 | 4.19 |
526.66 | 5.61 | 5.61 |
508.67 | 5.47 | 5.47 |
522.70 | 5.78 | 5.78 |
508.67 | 5.83 | 5.83 |
526.66 | 5.61 | 5.61 |
520.68 | 5.61 | 5.61 |
543.12 | 6.12 | 6.12 |
534.71 | 6.00 | 6.00 |
562.76 | 6.78 | 6.78 |
565.77 | 5.40 | 5.40 |
579.79 | 5.79 | 5.79 |
563.75 | 5.15 | 5.15 |
593.78 | 4.56 | 4.56 |
617.84 | 6.47 | 6.47 |
432.57 | 3.90 | 3.90 |
538.70 | 5.48 | 5.48 |
474.65 | 4.92 | 4.92 |
474.65 | 5.07 | 5.07 |
500.69 | 5.60 | 5.60 |
526.66 | 5.61 | 5.61 |
415.47 | 4.70 | 4.70 |
470.55 | 4.39 | 4.39 |
415.47 | 5.07 | 5.07 |
449.92 | 5.64 | 5.64 |
435.89 | 5.33 | 5.33 |
483.59 | 6.32 | 6.32 |
497.62 | 6.90 | 6.90 |
519.58 | 6.18 | 6.18 |
497.62 | 6.61 | 6.61 |
547.64 | 5.66 | 5.66 |
485.90 | 6.21 | 6.21 |
520.61 | 6.02 | 6.02 |
576.67 | 6.49 | 6.49 |
455.54 | 5.54 | 5.54 |
445.95 | 5.52 | 5.52 |
534.71 | 6.19 | 6.19 |
527.00 | 6.41 | 6.41 |
497.62 | 6.90 | 6.90 |
483.59 | 6.32 | 6.32 |
517.61 | 7.01 | 7.01 |
441.51 | 5.60 | 5.60 |
551.96 | 7.37 | 7.37 |
460.97 | 5.48 | 5.48 |
418.89 | 4.58 | 4.58 |
574.70 | 7.02 | 7.02 |
544.65 | 5.75 | 5.75 |
457.55 | 5.79 | 5.79 |
476.38 | 5.61 | 5.61 |
459.53 | 4.37 | 4.37 |
445.95 | 5.81 | 5.81 |
443.53 | 5.57 | 5.57 |
471.32 | 5.38 | 5.38 |
498.61 | 5.45 | 5.45 |
445.50 | 4.19 | 4.19 |
542.62 | 5.22 | 5.22 |
534.71 | 6.19 | 6.19 |
558.81 | 5.21 | 5.21 |
558.81 | 5.21 | 5.21 |
544.10 | 5.52 | 5.52 |
576.79 | 7.22 | 7.22 |
441.51 | 5.23 | 5.23 |
460.97 | 5.48 | 5.48 |
465.48 | 5.86 | 5.86 |
472.98 | 5.81 | 5.81 |
494.64 | 5.44 | 5.44 |
478.94 | 4.60 | 4.60 |
449.92 | 5.64 | 5.64 |
497.62 | 6.76 | 6.76 |
572.84 | 5.77 | 5.77 |
580.63 | 6.32 | 6.32 |
604.69 | 5.99 | 5.99 |
447.93 | 5.20 | 5.20 |
415.47 | 4.98 | 4.98 |
443.53 | 5.40 | 5.40 |
484.58 | 4.74 | 4.74 |
581.70 | 4.69 | 4.69 |
455.54 | 5.73 | 5.73 |
429.50 | 5.54 | 5.54 |
599.78 | 6.47 | 6.47 |
445.45 | 4.13 | 4.13 |
509.66 | 4.86 | 4.86 |
541.68 | 4.99 | 4.99 |
427.51 | 4.44 | 4.44 |
520.68 | 5.61 | 5.61 |
443.53 | 5.48 | 5.48 |
433.46 | 5.12 | 5.12 |
538.70 | 4.83 | 4.83 |
460.97 | 5.48 | 5.48 |
541.37 | 5.30 | 5.30 |
455.54 | 5.73 | 5.73 |
617.84 | 6.47 | 6.47 |
534.71 | 6.00 | 6.00 |
446.94 | 5.20 | 5.20 |
531.59 | 7.11 | 7.11 |
430.49 | 5.09 | 5.09 |
508.67 | 5.47 | 5.47 |
469.56 | 5.93 | 5.93 |
523.04 | 6.51 | 6.51 |
593.71 | 8.54 | 8.54 |
577.78 | 5.59 | 5.59 |
536.51 | 4.72 | 4.72 |
433.46 | 5.12 | 5.12 |
501.56 | 5.39 | 5.39 |
500.05 | 6.84 | 6.84 |
566.60 | 6.29 | 6.29 |
460.97 | 5.91 | 5.91 |
445.95 | 5.52 | 5.52 |
513.62 | 5.68 | 5.68 |
484.58 | 5.13 | 5.13 |
497.99 | 6.76 | 6.76 |
433.46 | 5.12 | 5.12 |
544.65 | 5.75 | 5.75 |
526.62 | 5.00 | 5.00 |
429.50 | 5.54 | 5.54 |
457.51 | 4.47 | 4.47 |
495.56 | 6.17 | 6.17 |
500.62 | 5.33 | 5.33 |
448.91 | 4.59 | 4.59 |
460.97 | 5.48 | 5.48 |
444.51 | 4.16 | 4.16 |
439.49 | 4.68 | 4.68 |
458.95 | 5.25 | 5.25 |
433.46 | 5.12 | 5.12 |
469.56 | 6.38 | 6.38 |
466.37 | 6.15 | 6.15 |
472.98 | 5.64 | 5.64 |
606.67 | 7.21 | 7.21 |
455.54 | 5.62 | 5.62 |
460.97 | 5.91 | 5.91 |
542.62 | 5.22 | 5.22 |
487.01 | 6.20 | 6.20 |
525.96 | 7.13 | 7.13 |
620.54 | 5.76 | 5.76 |
548.63 | 5.06 | 5.06 |
470.55 | 4.35 | 4.35 |
452.35 | 5.84 | 5.84 |
455.54 | 5.58 | 5.58 |
464.93 | 5.06 | 5.06 |
473.55 | 5.02 | 5.02 |
590.40 | 5.61 | 5.61 |
455.54 | 5.99 | 5.99 |
536.72 | 6.28 | 6.28 |
527.98 | 7.01 | 7.01 |
519.58 | 6.18 | 6.18 |
569.69 | 4.59 | 4.59 |
447.49 | 5.15 | 5.15 |
606.67 | 6.85 | 6.85 |
467.45 | 5.43 | 5.43 |
480.62 | 5.13 | 5.13 |
498.61 | 5.08 | 5.08 |
535.63 | 5.83 | 5.83 |
429.50 | 5.01 | 5.01 |
592.64 | 6.46 | 6.46 |
415.47 | 4.98 | 4.98 |
506.59 | 5.97 | 5.97 |
534.64 | 6.43 | 6.43 |
560.70 | 6.61 | 6.61 |
544.65 | 5.75 | 5.75 |
412.50 | 4.55 | 4.55 |
427.48 | 5.21 | 5.21 |
562.64 | 5.88 | 5.88 |
490.41 | 5.63 | 5.63 |
457.55 | 5.79 | 5.79 |
494.64 | 5.44 | 5.44 |
627.80 | 5.52 | 5.52 |
498.61 | 5.05 | 5.05 |
626.81 | 6.12 | 6.12 |
538.67 | 6.01 | 6.01 |
444.51 | 5.40 | 5.40 |
466.37 | 6.15 | 6.15 |
429.50 | 5.29 | 5.29 |
499.59 | 5.56 | 5.56 |
458.95 | 5.25 | 5.25 |
463.94 | 5.95 | 5.95 |
546.65 | 6.27 | 6.27 |
520.68 | 5.80 | 5.80 |
498.61 | 5.00 | 5.00 |
532.69 | 5.78 | 5.78 |
455.54 | 5.73 | 5.73 |
538.67 | 6.01 | 6.01 |
432.92 | 4.61 | 4.61 |
535.63 | 5.83 | 5.83 |
517.61 | 6.87 | 6.87 |
510.82 | 6.26 | 6.26 |
506.59 | 5.99 | 5.99 |
443.53 | 5.57 | 5.57 |
561.11 | 6.26 | 6.26 |
563.75 | 5.20 | 5.20 |
433.46 | 4.84 | 4.84 |
627.80 | 5.52 | 5.52 |
499.92 | 6.23 | 6.23 |
473.51 | 4.49 | 4.49 |
608.68 | 7.10 | 7.10 |
444.51 | 5.40 | 5.40 |
484.58 | 4.74 | 4.74 |
525.96 | 6.77 | 6.77 |
520.68 | 5.80 | 5.80 |
422.49 | 4.72 | 4.72 |
484.58 | 4.69 | 4.69 |
494.64 | 5.16 | 5.16 |
429.44 | 3.84 | 3.84 |
496.59 | 4.61 | 4.61 |
699.76 | 6.37 | 6.37 |
505.42 | 6.02 | 6.02 |
505.60 | 6.58 | 6.58 |
443.53 | 5.32 | 5.32 |
619.05 | 6.28 | 6.28 |
498.56 | 4.22 | 4.22 |
415.47 | 4.98 | 4.98 |
446.94 | 4.92 | 4.92 |
498.61 | 5.08 | 5.08 |
467.50 | 5.84 | 5.84 |
511.94 | 6.38 | 6.38 |
547.64 | 5.66 | 5.66 |
558.68 | 6.31 | 6.31 |
426.52 | 4.57 | 4.57 |
475.00 | 5.73 | 5.73 |
427.48 | 4.84 | 4.84 |
584.77 | 7.04 | 7.04 |
457.55 | 5.82 | 5.82 |
563.75 | 5.20 | 5.20 |
508.67 | 5.47 | 5.47 |