Basic Information
ID: ALA3883064
Type: Binding
Description: Inhibition of TCF-4/beta catenin in human Tcf22C11 cells expressing Tcf-4/SV40 binding sites driving firefly luciferase reporter gene after 24 hrs by luminometer
Organism: Homo sapiens
Cell type: Tcf22C11
Activity Charts
Bioactivity
Activity Types for Assay ALA3883064
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 415.47 | 4.98 | 4.98 |
| 484.58 | 4.69 | 4.69 |
| 431.93 | 5.50 | 5.50 |
| 432.92 | 4.89 | 4.89 |
| 401.45 | 4.68 | 4.68 |
| 418.89 | 4.58 | 4.58 |
| 432.92 | 4.89 | 4.89 |
| 471.54 | 4.78 | 4.78 |
| 417.90 | 5.19 | 5.19 |
| 415.47 | 4.98 | 4.98 |
| 415.47 | 4.98 | 4.98 |
| 469.56 | 5.93 | 5.93 |
| 541.37 | 5.30 | 5.30 |
| 459.55 | 6.20 | 6.20 |
| 440.48 | 4.57 | 4.57 |
| 457.51 | 4.90 | 4.90 |
| 432.92 | 4.89 | 4.89 |
| 418.89 | 4.58 | 4.58 |
| 429.50 | 5.01 | 5.01 |
| 470.55 | 4.35 | 4.35 |
| 459.53 | 4.75 | 4.75 |
| 443.48 | 4.51 | 4.51 |
| 443.53 | 5.76 | 5.76 |
| 445.50 | 4.19 | 4.19 |
| 472.57 | 4.76 | 4.76 |
| 441.51 | 5.15 | 5.15 |
| 441.51 | 5.34 | 5.34 |
| 443.53 | 5.26 | 5.26 |
| 451.45 | 5.55 | 5.55 |
| 417.90 | 5.19 | 5.19 |
| 415.47 | 4.98 | 4.98 |
| 431.93 | 5.50 | 5.50 |
| 484.58 | 4.74 | 4.74 |
| 408.47 | 4.41 | 4.41 |
| 397.48 | 4.84 | 4.84 |
| 498.61 | 5.13 | 5.13 |
| 431.93 | 5.50 | 5.50 |
| 431.93 | 5.50 | 5.50 |
| 455.54 | 5.54 | 5.54 |
| 561.11 | 6.26 | 6.26 |
| 498.63 | 5.06 | 5.06 |
| 498.64 | 4.19 | 4.19 |
| 526.66 | 5.61 | 5.61 |
| 508.67 | 5.47 | 5.47 |
| 522.70 | 5.78 | 5.78 |
| 508.67 | 5.83 | 5.83 |
| 526.66 | 5.61 | 5.61 |
| 520.68 | 5.61 | 5.61 |
| 543.12 | 6.12 | 6.12 |
| 534.71 | 6.00 | 6.00 |
| 562.76 | 6.78 | 6.78 |
| 565.77 | 5.40 | 5.40 |
| 579.79 | 5.79 | 5.79 |
| 563.75 | 5.15 | 5.15 |
| 593.78 | 4.56 | 4.56 |
| 617.84 | 6.47 | 6.47 |
| 432.57 | 3.90 | 3.90 |
| 538.70 | 5.48 | 5.48 |
| 474.65 | 4.92 | 4.92 |
| 474.65 | 5.07 | 5.07 |
| 500.69 | 5.60 | 5.60 |
| 526.66 | 5.61 | 5.61 |
| 415.47 | 4.70 | 4.70 |
| 470.55 | 4.39 | 4.39 |
| 415.47 | 5.07 | 5.07 |
| 449.92 | 5.64 | 5.64 |
| 435.89 | 5.33 | 5.33 |
| 483.59 | 6.32 | 6.32 |
| 497.62 | 6.90 | 6.90 |
| 519.58 | 6.18 | 6.18 |
| 497.62 | 6.61 | 6.61 |
| 547.64 | 5.66 | 5.66 |
| 485.90 | 6.21 | 6.21 |
| 520.61 | 6.02 | 6.02 |
| 576.67 | 6.49 | 6.49 |
| 455.54 | 5.54 | 5.54 |
| 445.95 | 5.52 | 5.52 |
| 534.71 | 6.19 | 6.19 |
| 527.00 | 6.41 | 6.41 |
| 497.62 | 6.90 | 6.90 |
| 483.59 | 6.32 | 6.32 |
| 517.61 | 7.01 | 7.01 |
| 441.51 | 5.60 | 5.60 |
| 551.96 | 7.37 | 7.37 |
| 460.97 | 5.48 | 5.48 |
| 418.89 | 4.58 | 4.58 |
| 574.70 | 7.02 | 7.02 |
| 544.65 | 5.75 | 5.75 |
| 457.55 | 5.79 | 5.79 |
| 476.38 | 5.61 | 5.61 |
| 459.53 | 4.37 | 4.37 |
| 445.95 | 5.81 | 5.81 |
| 443.53 | 5.57 | 5.57 |
| 471.32 | 5.38 | 5.38 |
| 498.61 | 5.45 | 5.45 |
| 445.50 | 4.19 | 4.19 |
| 542.62 | 5.22 | 5.22 |
| 534.71 | 6.19 | 6.19 |
| 558.81 | 5.21 | 5.21 |
| 558.81 | 5.21 | 5.21 |
| 544.10 | 5.52 | 5.52 |
| 576.79 | 7.22 | 7.22 |
| 441.51 | 5.23 | 5.23 |
| 460.97 | 5.48 | 5.48 |
| 465.48 | 5.86 | 5.86 |
| 472.98 | 5.81 | 5.81 |
| 494.64 | 5.44 | 5.44 |
| 478.94 | 4.60 | 4.60 |
| 449.92 | 5.64 | 5.64 |
| 497.62 | 6.76 | 6.76 |
| 572.84 | 5.77 | 5.77 |
| 580.63 | 6.32 | 6.32 |
| 604.69 | 5.99 | 5.99 |
| 447.93 | 5.20 | 5.20 |
| 415.47 | 4.98 | 4.98 |
| 443.53 | 5.40 | 5.40 |
| 484.58 | 4.74 | 4.74 |
| 581.70 | 4.69 | 4.69 |
| 455.54 | 5.73 | 5.73 |
| 429.50 | 5.54 | 5.54 |
| 599.78 | 6.47 | 6.47 |
| 445.45 | 4.13 | 4.13 |
| 509.66 | 4.86 | 4.86 |
| 541.68 | 4.99 | 4.99 |
| 427.51 | 4.44 | 4.44 |
| 520.68 | 5.61 | 5.61 |
| 443.53 | 5.48 | 5.48 |
| 433.46 | 5.12 | 5.12 |
| 538.70 | 4.83 | 4.83 |
| 460.97 | 5.48 | 5.48 |
| 541.37 | 5.30 | 5.30 |
| 455.54 | 5.73 | 5.73 |
| 617.84 | 6.47 | 6.47 |
| 534.71 | 6.00 | 6.00 |
| 446.94 | 5.20 | 5.20 |
| 531.59 | 7.11 | 7.11 |
| 430.49 | 5.09 | 5.09 |
| 508.67 | 5.47 | 5.47 |
| 469.56 | 5.93 | 5.93 |
| 523.04 | 6.51 | 6.51 |
| 593.71 | 8.54 | 8.54 |
| 577.78 | 5.59 | 5.59 |
| 536.51 | 4.72 | 4.72 |
| 433.46 | 5.12 | 5.12 |
| 501.56 | 5.39 | 5.39 |
| 500.05 | 6.84 | 6.84 |
| 566.60 | 6.29 | 6.29 |
| 460.97 | 5.91 | 5.91 |
| 445.95 | 5.52 | 5.52 |
| 513.62 | 5.68 | 5.68 |
| 484.58 | 5.13 | 5.13 |
| 497.99 | 6.76 | 6.76 |
| 433.46 | 5.12 | 5.12 |
| 544.65 | 5.75 | 5.75 |
| 526.62 | 5.00 | 5.00 |
| 429.50 | 5.54 | 5.54 |
| 457.51 | 4.47 | 4.47 |
| 495.56 | 6.17 | 6.17 |
| 500.62 | 5.33 | 5.33 |
| 448.91 | 4.59 | 4.59 |
| 460.97 | 5.48 | 5.48 |
| 444.51 | 4.16 | 4.16 |
| 439.49 | 4.68 | 4.68 |
| 458.95 | 5.25 | 5.25 |
| 433.46 | 5.12 | 5.12 |
| 469.56 | 6.38 | 6.38 |
| 466.37 | 6.15 | 6.15 |
| 472.98 | 5.64 | 5.64 |
| 606.67 | 7.21 | 7.21 |
| 455.54 | 5.62 | 5.62 |
| 460.97 | 5.91 | 5.91 |
| 542.62 | 5.22 | 5.22 |
| 487.01 | 6.20 | 6.20 |
| 525.96 | 7.13 | 7.13 |
| 620.54 | 5.76 | 5.76 |
| 548.63 | 5.06 | 5.06 |
| 470.55 | 4.35 | 4.35 |
| 452.35 | 5.84 | 5.84 |
| 455.54 | 5.58 | 5.58 |
| 464.93 | 5.06 | 5.06 |
| 473.55 | 5.02 | 5.02 |
| 590.40 | 5.61 | 5.61 |
| 455.54 | 5.99 | 5.99 |
| 536.72 | 6.28 | 6.28 |
| 527.98 | 7.01 | 7.01 |
| 519.58 | 6.18 | 6.18 |
| 569.69 | 4.59 | 4.59 |
| 447.49 | 5.15 | 5.15 |
| 606.67 | 6.85 | 6.85 |
| 467.45 | 5.43 | 5.43 |
| 480.62 | 5.13 | 5.13 |
| 498.61 | 5.08 | 5.08 |
| 535.63 | 5.83 | 5.83 |
| 429.50 | 5.01 | 5.01 |
| 592.64 | 6.46 | 6.46 |
| 415.47 | 4.98 | 4.98 |
| 506.59 | 5.97 | 5.97 |
| 534.64 | 6.43 | 6.43 |
| 560.70 | 6.61 | 6.61 |
| 544.65 | 5.75 | 5.75 |
| 412.50 | 4.55 | 4.55 |
| 427.48 | 5.21 | 5.21 |
| 562.64 | 5.88 | 5.88 |
| 490.41 | 5.63 | 5.63 |
| 457.55 | 5.79 | 5.79 |
| 494.64 | 5.44 | 5.44 |
| 627.80 | 5.52 | 5.52 |
| 498.61 | 5.05 | 5.05 |
| 626.81 | 6.12 | 6.12 |
| 538.67 | 6.01 | 6.01 |
| 444.51 | 5.40 | 5.40 |
| 466.37 | 6.15 | 6.15 |
| 429.50 | 5.29 | 5.29 |
| 499.59 | 5.56 | 5.56 |
| 458.95 | 5.25 | 5.25 |
| 463.94 | 5.95 | 5.95 |
| 546.65 | 6.27 | 6.27 |
| 520.68 | 5.80 | 5.80 |
| 498.61 | 5.00 | 5.00 |
| 532.69 | 5.78 | 5.78 |
| 455.54 | 5.73 | 5.73 |
| 538.67 | 6.01 | 6.01 |
| 432.92 | 4.61 | 4.61 |
| 535.63 | 5.83 | 5.83 |
| 517.61 | 6.87 | 6.87 |
| 510.82 | 6.26 | 6.26 |
| 506.59 | 5.99 | 5.99 |
| 443.53 | 5.57 | 5.57 |
| 561.11 | 6.26 | 6.26 |
| 563.75 | 5.20 | 5.20 |
| 433.46 | 4.84 | 4.84 |
| 627.80 | 5.52 | 5.52 |
| 499.92 | 6.23 | 6.23 |
| 473.51 | 4.49 | 4.49 |
| 608.68 | 7.10 | 7.10 |
| 444.51 | 5.40 | 5.40 |
| 484.58 | 4.74 | 4.74 |
| 525.96 | 6.77 | 6.77 |
| 520.68 | 5.80 | 5.80 |
| 422.49 | 4.72 | 4.72 |
| 484.58 | 4.69 | 4.69 |
| 494.64 | 5.16 | 5.16 |
| 429.44 | 3.84 | 3.84 |
| 496.59 | 4.61 | 4.61 |
| 699.76 | 6.37 | 6.37 |
| 505.42 | 6.02 | 6.02 |
| 505.60 | 6.58 | 6.58 |
| 443.53 | 5.32 | 5.32 |
| 619.05 | 6.28 | 6.28 |
| 498.56 | 4.22 | 4.22 |
| 415.47 | 4.98 | 4.98 |
| 446.94 | 4.92 | 4.92 |
| 498.61 | 5.08 | 5.08 |
| 467.50 | 5.84 | 5.84 |
| 511.94 | 6.38 | 6.38 |
| 547.64 | 5.66 | 5.66 |
| 558.68 | 6.31 | 6.31 |
| 426.52 | 4.57 | 4.57 |
| 475.00 | 5.73 | 5.73 |
| 427.48 | 4.84 | 4.84 |
| 584.77 | 7.04 | 7.04 |
| 457.55 | 5.82 | 5.82 |
| 563.75 | 5.20 | 5.20 |
| 508.67 | 5.47 | 5.47 |