Inhibition of TCF-4/beta catenin in human Tcf22C11 cells expressing Tcf-4/SV40 binding sites driving firefly luciferase reporter gene after 24 hrs by ...

Basic Information

ID: ALA3883064

Type: Binding

Description: Inhibition of TCF-4/beta catenin in human Tcf22C11 cells expressing Tcf-4/SV40 binding sites driving firefly luciferase reporter gene after 24 hrs by luminometer

Format: BAO_0000219

Organism: Homo sapiens

Cell type: Tcf22C11

Target: TCF4/beta-catenin(ALA3038511)

Document: ALA3882728

Inhibition of TCF-4/beta catenin in human Tcf22C11 cells expressing Tcf-4/SV40 binding sites driving firefly luciferase reporter gene after 24 hrs by luminometer: 38

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3883064

IC50

Total(264)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
415.47	4.98	4.98
484.58	4.69	4.69
431.93	5.50	5.50
432.92	4.89	4.89
401.45	4.68	4.68
418.89	4.58	4.58
432.92	4.89	4.89
471.54	4.78	4.78
417.90	5.19	5.19
415.47	4.98	4.98
415.47	4.98	4.98
469.56	5.93	5.93
541.37	5.30	5.30
459.55	6.20	6.20
440.48	4.57	4.57
457.51	4.90	4.90
432.92	4.89	4.89
418.89	4.58	4.58
429.50	5.01	5.01
470.55	4.35	4.35
459.53	4.75	4.75
443.48	4.51	4.51
443.53	5.76	5.76
445.50	4.19	4.19
472.57	4.76	4.76
441.51	5.15	5.15
441.51	5.34	5.34
443.53	5.26	5.26
451.45	5.55	5.55
417.90	5.19	5.19
415.47	4.98	4.98
431.93	5.50	5.50
484.58	4.74	4.74
408.47	4.41	4.41
397.48	4.84	4.84
498.61	5.13	5.13
431.93	5.50	5.50
431.93	5.50	5.50
455.54	5.54	5.54
561.11	6.26	6.26
498.63	5.06	5.06
498.64	4.19	4.19
526.66	5.61	5.61
508.67	5.47	5.47
522.70	5.78	5.78
508.67	5.83	5.83
526.66	5.61	5.61
520.68	5.61	5.61
543.12	6.12	6.12
534.71	6.00	6.00
562.76	6.78	6.78
565.77	5.40	5.40
579.79	5.79	5.79
563.75	5.15	5.15
593.78	4.56	4.56
617.84	6.47	6.47
432.57	3.90	3.90
538.70	5.48	5.48
474.65	4.92	4.92
474.65	5.07	5.07
500.69	5.60	5.60
526.66	5.61	5.61
415.47	4.70	4.70
470.55	4.39	4.39
415.47	5.07	5.07
449.92	5.64	5.64
435.89	5.33	5.33
483.59	6.32	6.32
497.62	6.90	6.90
519.58	6.18	6.18
497.62	6.61	6.61
547.64	5.66	5.66
485.90	6.21	6.21
520.61	6.02	6.02
576.67	6.49	6.49
455.54	5.54	5.54
445.95	5.52	5.52
534.71	6.19	6.19
527.00	6.41	6.41
497.62	6.90	6.90
483.59	6.32	6.32
517.61	7.01	7.01
441.51	5.60	5.60
551.96	7.37	7.37
460.97	5.48	5.48
418.89	4.58	4.58
574.70	7.02	7.02
544.65	5.75	5.75
457.55	5.79	5.79
476.38	5.61	5.61
459.53	4.37	4.37
445.95	5.81	5.81
443.53	5.57	5.57
471.32	5.38	5.38
498.61	5.45	5.45
445.50	4.19	4.19
542.62	5.22	5.22
534.71	6.19	6.19
558.81	5.21	5.21
558.81	5.21	5.21
544.10	5.52	5.52
576.79	7.22	7.22
441.51	5.23	5.23
460.97	5.48	5.48
465.48	5.86	5.86
472.98	5.81	5.81
494.64	5.44	5.44
478.94	4.60	4.60
449.92	5.64	5.64
497.62	6.76	6.76
572.84	5.77	5.77
580.63	6.32	6.32
604.69	5.99	5.99
447.93	5.20	5.20
415.47	4.98	4.98
443.53	5.40	5.40
484.58	4.74	4.74
581.70	4.69	4.69
455.54	5.73	5.73
429.50	5.54	5.54
599.78	6.47	6.47
445.45	4.13	4.13
509.66	4.86	4.86
541.68	4.99	4.99
427.51	4.44	4.44
520.68	5.61	5.61
443.53	5.48	5.48
433.46	5.12	5.12
538.70	4.83	4.83
460.97	5.48	5.48
541.37	5.30	5.30
455.54	5.73	5.73
617.84	6.47	6.47
534.71	6.00	6.00
446.94	5.20	5.20
531.59	7.11	7.11
430.49	5.09	5.09
508.67	5.47	5.47
469.56	5.93	5.93
523.04	6.51	6.51
593.71	8.54	8.54
577.78	5.59	5.59
536.51	4.72	4.72
433.46	5.12	5.12
501.56	5.39	5.39
500.05	6.84	6.84
566.60	6.29	6.29
460.97	5.91	5.91
445.95	5.52	5.52
513.62	5.68	5.68
484.58	5.13	5.13
497.99	6.76	6.76
433.46	5.12	5.12
544.65	5.75	5.75
526.62	5.00	5.00
429.50	5.54	5.54
457.51	4.47	4.47
495.56	6.17	6.17
500.62	5.33	5.33
448.91	4.59	4.59
460.97	5.48	5.48
444.51	4.16	4.16
439.49	4.68	4.68
458.95	5.25	5.25
433.46	5.12	5.12
469.56	6.38	6.38
466.37	6.15	6.15
472.98	5.64	5.64
606.67	7.21	7.21
455.54	5.62	5.62
460.97	5.91	5.91
542.62	5.22	5.22
487.01	6.20	6.20
525.96	7.13	7.13
620.54	5.76	5.76
548.63	5.06	5.06
470.55	4.35	4.35
452.35	5.84	5.84
455.54	5.58	5.58
464.93	5.06	5.06
473.55	5.02	5.02
590.40	5.61	5.61
455.54	5.99	5.99
536.72	6.28	6.28
527.98	7.01	7.01
519.58	6.18	6.18
569.69	4.59	4.59
447.49	5.15	5.15
606.67	6.85	6.85
467.45	5.43	5.43
480.62	5.13	5.13
498.61	5.08	5.08
535.63	5.83	5.83
429.50	5.01	5.01
592.64	6.46	6.46
415.47	4.98	4.98
506.59	5.97	5.97
534.64	6.43	6.43
560.70	6.61	6.61
544.65	5.75	5.75
412.50	4.55	4.55
427.48	5.21	5.21
562.64	5.88	5.88
490.41	5.63	5.63
457.55	5.79	5.79
494.64	5.44	5.44
627.80	5.52	5.52
498.61	5.05	5.05
626.81	6.12	6.12
538.67	6.01	6.01
444.51	5.40	5.40
466.37	6.15	6.15
429.50	5.29	5.29
499.59	5.56	5.56
458.95	5.25	5.25
463.94	5.95	5.95
546.65	6.27	6.27
520.68	5.80	5.80
498.61	5.00	5.00
532.69	5.78	5.78
455.54	5.73	5.73
538.67	6.01	6.01
432.92	4.61	4.61
535.63	5.83	5.83
517.61	6.87	6.87
510.82	6.26	6.26
506.59	5.99	5.99
443.53	5.57	5.57
561.11	6.26	6.26
563.75	5.20	5.20
433.46	4.84	4.84
627.80	5.52	5.52
499.92	6.23	6.23
473.51	4.49	4.49
608.68	7.10	7.10
444.51	5.40	5.40
484.58	4.74	4.74
525.96	6.77	6.77
520.68	5.80	5.80
422.49	4.72	4.72
484.58	4.69	4.69
494.64	5.16	5.16
429.44	3.84	3.84
496.59	4.61	4.61
699.76	6.37	6.37
505.42	6.02	6.02
505.60	6.58	6.58
443.53	5.32	5.32
619.05	6.28	6.28
498.56	4.22	4.22
415.47	4.98	4.98
446.94	4.92	4.92
498.61	5.08	5.08
467.50	5.84	5.84
511.94	6.38	6.38
547.64	5.66	5.66
558.68	6.31	6.31
426.52	4.57	4.57
475.00	5.73	5.73
427.48	4.84	4.84
584.77	7.04	7.04
457.55	5.82	5.82
563.75	5.20	5.20
508.67	5.47	5.47