Basic Information
ID: ALA3883067
Type: Binding
Description: Inhibition of recombinant human N-terminal GST His6-tagged thrombin cleavage site-fused EGFR (H672 to A1210 residues) expressed in baculovirus using poly-EY as substrate after 210 mins by luciferase coupled chemiluminescence assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Epidermal growth factor receptor erbB1(ALA203)
Document: ALA3882729
Inhibition of recombinant human N-terminal GST His6-tagged thrombin cleavage site-fused EGFR (H672 to A1210 residues) expressed in baculovirus using poly-EY as substrate after 210 mins by luciferase coupled chemiluminescence assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3883067
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 491.39 | 5.79 | 5.79 |
| 492.36 | 4.50 | 4.50 |
| 509.37 | 4.31 | 4.31 |
| 557.23 | 5.36 | 5.36 |
| 502.37 | 4.01 | 4.01 |
| 510.41 | 6.79 | 6.79 |
| 493.37 | 5.07 | 5.07 |
| 530.48 | 6.53 | 6.53 |
| 520.39 | 4.56 | 4.56 |
| 602.48 | 5.71 | 5.71 |
| 601.49 | 7.11 | 7.11 |
| 433.34 | 5.16 | 5.16 |
| 570.27 | 4.93 | 4.93 |
| 536.81 | 4.75 | 4.75 |
| 447.37 | 5.55 | 5.55 |
| 509.37 | 4.31 | 4.31 |
| 509.35 | 5.36 | 5.36 |
| 522.78 | 4.36 | 4.36 |
| 545.50 | 5.47 | 5.47 |
| 463.32 | 3.93 | 3.93 |
| 553.82 | 4.42 | 4.42 |
| 510.41 | 6.79 | 6.79 |
| 475.38 | 4.93 | 4.93 |
| 493.42 | 4.84 | 4.84 |
| 478.33 | 4.60 | 4.60 |
| 404.30 | 5.87 | 5.87 |
| 459.38 | 5.41 | 5.41 |
| 558.76 | 4.95 | 4.95 |
| 476.91 | 4.56 | 4.56 |
| 580.54 | 8.24 | 8.24 |
| 518.43 | 5.56 | 5.56 |
| 553.82 | 4.42 | 4.42 |
| 496.32 | 4.74 | 4.74 |
| 554.27 | 5.69 | 5.69 |
| 420.30 | 5.25 | 5.25 |
| 553.82 | 4.42 | 4.42 |
| 390.27 | 5.48 | 5.48 |
| 475.38 | 4.93 | 4.93 |
| 516.84 | 8.14 | 8.14 |
| 436.30 | 4.83 | 4.83 |
| 522.78 | 4.36 | 4.36 |
| 510.35 | 4.64 | 4.64 |
| 475.38 | 4.93 | 4.93 |
| 492.76 | 4.73 | 4.73 |
| 524.36 | 6.33 | 6.33 |
| 571.26 | 5.26 | 5.26 |
| 503.35 | 4.49 | 4.49 |
| 463.37 | 4.79 | 4.79 |
| 513.34 | 5.92 | 5.92 |
| 520.39 | 4.56 | 4.56 |
| 532.45 | 5.56 | 5.56 |
| 491.38 | 4.17 | 4.17 |
| 568.44 | 6.20 | 6.20 |
| 506.37 | 4.17 | 4.17 |
| 488.40 | 5.37 | 5.37 |
| 516.45 | 6.19 | 6.19 |
| 492.91 | 3.79 | 3.79 |
| 540.77 | 4.84 | 4.84 |
| 506.37 | 4.17 | 4.17 |
| 512.35 | 2.52 | 2.52 |
| 450.32 | 5.22 | 5.22 |
| 550.45 | 7.62 | 7.62 |
| 449.34 | 4.40 | 4.40 |
| 404.30 | 6.01 | 6.01 |
| 559.52 | 5.86 | 5.86 |
| 529.43 | 6.20 | 6.20 |
| 432.35 | 6.65 | 6.65 |
| 461.88 | 3.73 | 3.73 |
| 479.87 | 4.22 | 4.22 |
| 578.52 | 7.99 | 7.99 |
| 492.91 | 3.79 | 3.79 |
| 502.36 | 4.06 | 4.06 |
| 512.78 | 5.25 | 5.25 |
| 601.49 | 6.77 | 6.77 |
| 457.91 | 3.90 | 3.90 |
| 553.82 | 4.42 | 4.42 |
| 493.37 | 5.07 | 5.07 |
| 516.39 | 4.40 | 4.40 |
| 461.31 | 4.72 | 4.72 |
| 540.77 | 4.84 | 4.84 |
| 537.82 | 5.18 | 5.18 |
| 543.86 | 8.04 | 8.04 |
| 478.33 | 4.25 | 4.25 |
| 550.79 | 4.43 | 4.43 |
| 568.30 | 6.08 | 6.08 |
| 433.32 | 5.72 | 5.72 |
| 537.82 | 5.18 | 5.18 |
| 449.34 | 4.40 | 4.40 |
| 509.37 | 4.31 | 4.31 |
| 510.41 | 6.79 | 6.79 |
| 530.42 | 4.79 | 4.79 |
| 509.37 | 4.31 | 4.31 |
| 475.38 | 4.93 | 4.93 |
| 446.38 | 7.04 | 7.04 |
| 577.42 | 8.41 | 8.41 |
| 520.39 | 4.51 | 4.51 |
| 538.39 | 6.37 | 6.37 |
| 524.36 | 6.33 | 6.33 |
| 550.82 | 4.28 | 4.28 |
| 496.32 | 4.74 | 4.74 |