Basic Information
ID: ALA3883070
Type: Binding
Description: Inhibition of recombinant human N-terminal GST-tagged factor 10a cleavage site-fused Flt1 (K784 to I1338 residues) expressed in baculovirus infected insect Sf9 cells using poly-EY as substrate after 120 mins in presence of gamma33P-ATP by liquid scintillation spectrometry
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Vascular endothelial growth factor receptor 1(ALA1868)
Document: ALA3882729
Inhibition of recombinant human N-terminal GST-tagged factor 10a cleavage site-fused Flt1 (K784 to I1338 residues) expressed in baculovirus infected insect Sf9 cells using poly-EY as substrate after 120 mins in presence of gamma33P-ATP by liquid scintillation spectrometry: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3883070
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 491.39 | 5.79 | 5.79 |
| 492.36 | 4.50 | 4.50 |
| 509.37 | 4.31 | 4.31 |
| 557.23 | 5.36 | 5.36 |
| 502.37 | 4.01 | 4.01 |
| 493.37 | 5.07 | 5.07 |
| 520.39 | 4.56 | 4.56 |
| 570.27 | 4.93 | 4.93 |
| 536.81 | 4.75 | 4.75 |
| 509.37 | 4.31 | 4.31 |
| 522.78 | 4.36 | 4.36 |
| 553.82 | 4.42 | 4.42 |
| 475.38 | 4.93 | 4.93 |
| 493.42 | 4.84 | 4.84 |
| 478.33 | 4.60 | 4.60 |
| 459.38 | 5.41 | 5.41 |
| 558.76 | 4.95 | 4.95 |
| 476.91 | 4.56 | 4.56 |
| 553.82 | 4.42 | 4.42 |
| 496.32 | 4.74 | 4.74 |
| 554.27 | 5.69 | 5.69 |
| 553.82 | 4.42 | 4.42 |
| 475.38 | 4.93 | 4.93 |
| 522.78 | 4.36 | 4.36 |
| 510.35 | 4.64 | 4.64 |
| 475.38 | 4.93 | 4.93 |
| 492.76 | 4.73 | 4.73 |
| 571.26 | 5.26 | 5.26 |
| 520.39 | 4.56 | 4.56 |
| 491.38 | 4.17 | 4.17 |
| 506.37 | 4.17 | 4.17 |
| 492.91 | 3.79 | 3.79 |
| 540.77 | 4.84 | 4.84 |
| 506.37 | 4.17 | 4.17 |
| 461.88 | 3.73 | 3.73 |
| 479.87 | 4.22 | 4.22 |
| 492.91 | 3.79 | 3.79 |
| 512.78 | 5.25 | 5.25 |
| 457.91 | 3.90 | 3.90 |
| 553.82 | 4.42 | 4.42 |
| 493.37 | 5.07 | 5.07 |
| 540.77 | 4.84 | 4.84 |
| 537.82 | 5.18 | 5.18 |
| 478.33 | 4.25 | 4.25 |
| 550.79 | 4.43 | 4.43 |
| 427.29 | 5.66 | 5.66 |
| 568.30 | 6.08 | 6.08 |
| 433.32 | 5.72 | 5.72 |
| 537.82 | 5.18 | 5.18 |
| 509.37 | 4.31 | 4.31 |
| 509.37 | 4.31 | 4.31 |
| 475.38 | 4.93 | 4.93 |
| 520.39 | 4.51 | 4.51 |
| 550.82 | 4.28 | 4.28 |
| 496.32 | 4.74 | 4.74 |