Inhibition of COX2 in C57BL/6 mouse peritoneal macrophages assessed as reduction in PGE2 formation pre-incubated for 2 hrs before LPS stimulation for ...

Basic Information

ID: ALA3883077

Type: Binding

Description: Inhibition of COX2 in C57BL/6 mouse peritoneal macrophages assessed as reduction in PGE2 formation pre-incubated for 2 hrs before LPS stimulation for 16 hrs followed by arachidonic acid addition and measured after 10 mins in presence of 500 uM aspirin by radio-immuno assay or enzyme-immunoassay

Format: BAO_0000357

Organism: Mus musculus

Strain: C57BL/6

Target:  Cyclooxygenase-2(ALA4321)

Document:  ALA3882732

Inhibition of COX2 in C57BL/6 mouse peritoneal macrophages assessed as reduction in PGE2 formation pre-incubated for 2 hrs before LPS stimulation for 16 hrs followed by arachidonic acid addition and measured after 10 mins in presence of 500 uM aspirin by radio-immuno assay or enzyme-immunoassay: 38

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
384.504.294.29
378.403.613.61
360.413.483.48
376.863.993.99
376.863.993.99
410.414.364.36
384.453.543.54
378.403.613.61
384.504.464.46
378.403.613.61
411.314.644.64
384.504.464.46
386.473.393.39
372.443.343.34
362.403.953.95
361.392.722.72
397.373.003.00
379.382.862.86
378.403.613.61
379.382.862.86
377.853.233.23
361.392.722.72
360.413.483.48
410.544.994.99
384.504.424.42
438.475.145.14
379.382.862.86
348.453.403.40
397.373.003.00
332.382.932.93
372.443.343.34
347.401.311.31
333.372.172.17
384.453.543.54
398.524.684.68
396.393.753.75
378.403.613.61
394.854.134.13
394.854.134.13
360.413.483.48
368.453.873.87
382.484.184.18
356.443.733.73
396.393.753.75
402.443.253.25
357.432.922.92
394.854.134.13
395.843.373.37
358.423.043.04
422.914.914.91
348.453.403.40
397.373.003.00
444.865.015.01
385.442.782.78
403.533.693.69
403.462.602.60
412.293.893.89
403.462.602.60
344.413.813.81
379.382.862.86
344.413.813.81
387.413.243.24
379.382.862.86
395.843.373.37
358.423.043.04
396.393.753.75
379.382.862.86
360.392.742.74
399.473.173.17
363.463.033.03
418.494.264.26
412.844.274.27
310.424.654.65
390.433.483.48
418.903.763.76
362.473.713.71
378.403.613.61
412.514.324.32
357.433.123.12
376.463.213.21
344.413.813.81
439.304.244.24
373.432.592.59
344.865.315.31
418.515.005.00
359.402.292.29
362.403.953.95
387.462.982.98
361.392.722.72
428.404.494.49
376.504.104.10
356.443.643.64
398.524.634.63
360.413.483.48
396.393.753.75
374.433.783.78
396.393.753.75
412.293.893.89
395.843.373.37
404.434.154.15