Basic Information
ID: ALA3883092
Type: Functional
Description: Agonist activity at human recombinant EP3A receptor expressed in HEK293 cells assessed as effect on calcium accumulation by Fluo-4 AM dye based FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Prostanoid EP3 receptor(ALA3710)
Document: ALA3882734
Agonist activity at human recombinant EP3A receptor expressed in HEK293 cells assessed as effect on calcium accumulation by Fluo-4 AM dye based FLIPR assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA3883092
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 465.07 | 6.28 | 6.28 |
| 358.48 | 4.22 | 4.22 |
| 371.43 | 3.99 | 3.99 |
| 431.55 | 4.77 | 4.77 |
| 360.45 | 3.12 | 3.12 |
| 425.01 | 5.35 | 5.35 |
| 374.48 | 3.21 | 3.21 |
| 378.94 | 5.26 | 5.26 |
| 394.94 | 4.65 | 4.65 |
| 411.50 | 4.57 | 4.57 |
| 394.98 | 5.57 | 5.57 |
| 451.05 | 5.89 | 5.89 |
| 332.44 | 3.54 | 3.54 |
| 387.43 | 3.38 | 3.38 |
| 435.00 | 5.57 | 5.57 |
| 435.48 | 3.97 | 3.97 |
| 403.50 | 3.99 | 3.99 |
| 318.41 | 3.45 | 3.45 |
| 387.50 | 4.46 | 4.46 |
| 380.91 | 4.16 | 4.16 |
| 428.61 | 6.27 | 6.27 |
| 372.46 | 2.99 | 2.99 |
| 392.92 | 4.33 | 4.33 |
| 374.52 | 4.53 | 4.53 |
| 480.60 | 4.52 | 4.52 |
| 384.52 | 4.87 | 4.87 |
| 442.60 | 5.01 | 5.01 |
| 414.54 | 4.54 | 4.54 |
| 389.47 | 3.60 | 3.60 |
| 376.49 | 3.42 | 3.42 |
| 466.57 | 4.43 | 4.43 |
| 400.56 | 5.79 | 5.79 |
| 408.97 | 5.04 | 5.04 |
| 428.57 | 4.62 | 4.62 |
| 427.57 | 5.73 | 5.73 |
| 429.54 | 4.92 | 4.92 |
| 396.96 | 4.45 | 4.45 |
| 451.05 | 6.19 | 6.19 |
| 414.59 | 6.18 | 6.18 |
| 436.98 | 4.42 | 4.42 |
| 425.53 | 4.71 | 4.71 |
| 408.97 | 4.64 | 4.64 |
| 477.09 | 6.44 | 6.44 |
| 415.49 | 4.30 | 4.30 |
| 437.02 | 5.80 | 5.80 |
| 345.48 | 4.90 | 4.90 |
| 360.49 | 4.44 | 4.44 |
| 352.86 | 3.45 | 3.45 |
| 428.57 | 4.93 | 4.93 |
| 414.59 | 5.88 | 5.88 |
| 378.94 | 4.76 | 4.76 |
| 388.50 | 3.61 | 3.61 |
| 412.57 | 5.95 | 5.95 |
| 412.57 | 5.65 | 5.65 |
| 358.48 | 3.72 | 3.72 |
| 443.61 | 5.97 | 5.97 |
| 394.94 | 4.25 | 4.25 |
| 416.56 | 4.76 | 4.76 |
| 430.59 | 4.85 | 4.85 |
| 410.98 | 4.54 | 4.54 |
| 434.96 | 3.87 | 3.87 |
| 372.51 | 4.31 | 4.31 |
| 444.61 | 5.24 | 5.24 |
| 421.02 | 6.31 | 6.31 |
| 448.99 | 3.96 | 3.96 |
| 358.43 | 2.90 | 2.90 |
| 356.51 | 5.34 | 5.34 |
| 380.96 | 5.48 | 5.48 |
| 427.57 | 5.35 | 5.35 |
| 374.48 | 3.52 | 3.52 |
| 342.48 | 5.25 | 5.25 |
| 423.04 | 6.35 | 6.35 |
| 451.00 | 4.51 | 4.51 |
| 406.95 | 4.42 | 4.42 |
| 449.03 | 5.96 | 5.96 |
| 392.97 | 5.35 | 5.35 |
| 435.05 | 6.39 | 6.39 |
| 427.59 | 4.33 | 4.33 |
| 394.94 | 4.56 | 4.56 |
| 471.64 | 3.95 | 3.95 |
| 370.45 | 3.14 | 3.14 |
| 453.02 | 4.73 | 4.73 |
| 429.58 | 5.58 | 5.58 |
| 430.59 | 5.15 | 5.15 |
| 394.94 | 4.23 | 4.23 |
| 438.99 | 4.64 | 4.64 |
| 426.60 | 6.04 | 6.04 |
| 417.53 | 4.38 | 4.38 |
| 364.91 | 4.67 | 4.67 |
| 412.57 | 5.95 | 5.95 |
| 445.58 | 5.16 | 5.16 |
| 386.49 | 3.38 | 3.38 |
| 449.03 | 5.96 | 5.96 |
| 410.98 | 5.26 | 5.26 |
| 501.06 | 5.56 | 5.56 |
| 463.06 | 6.05 | 6.05 |
| 455.64 | 4.93 | 4.93 |
| 372.46 | 3.29 | 3.29 |
| 487.04 | 5.47 | 5.47 |
| 398.54 | 5.56 | 5.56 |