ID: ALA3883177
Type: Binding
Description: Inhibition of DDAH in mouse MLE12 cells assessed as decrease in serum-stimulated cell proliferation at 3 to 100 uM preincubated for 2 hrs followed by fetal bovine serum addition measured 24 hrs post compound treatment by BrdU incorporation assay
Format: BAO_0000219
Organism: Mus musculus
Cell type: MLE12
Target: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1(ALA3988621)
Document: ALA3882738
Inhibition of DDAH in mouse MLE12 cells assessed as decrease in serum-stimulated cell proliferation at 3 to 100 uM preincubated for 2 hrs followed by fetal bovine serum addition measured 24 hrs post compound treatment by BrdU incorporation assay: 38
Bioactivity
Activity Types for Assay ALA3883177
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
345.42 | 2.90 | 2.90 |