Inhibition of DDAH in mouse MLE12 cells assessed as decrease in serum-stimulated cell proliferation at 50 to 100 uM preincubated for 2 hrs followed by...

Basic Information

ID: ALA3883179

Type: Binding

Description: Inhibition of DDAH in mouse MLE12 cells assessed as decrease in serum-stimulated cell proliferation at 50 to 100 uM preincubated for 2 hrs followed by fetal bovine serum addition measured 24 hrs post compound treatment by BrdU incorporation assay

Format: BAO_0000219

Organism: Mus musculus

Cell type: MLE12

Target:  N(G),N(G)-dimethylarginine dimethylaminohydrolase 1(ALA3988621)

Document:  ALA3882738

Inhibition of DDAH in mouse MLE12 cells assessed as decrease in serum-stimulated cell proliferation at 50 to 100 uM preincubated for 2 hrs followed by fetal bovine serum addition measured 24 hrs post compound treatment by BrdU incorporation assay: 38

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
232.28-1.06-1.06