Basic Information
ID: ALA3887052
Type: Binding
Description: Inhibition Assay: Inhibition of human alpha-FXIIa was determined by the method described in [0092]-[0098] using activated human alpha-Factor XII (activated Hageman Factor) from Enzyme Research Laboratories at 50 mPEU/mL and CHA-Gly-Arg-pNA at 2 mM, 1 mM, and 0.5 mM as substrate; results are reported as Ki values (nanomolar).
Activity Charts
Bioactivity
Activity Types for Assay ALA3887052
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 681.90 | 2.38 | 2.38 |
| 707.94 | 2.77 | 2.77 |
| 695.93 | 2.77 | 2.77 |
| 695.93 | 2.77 | 2.77 |
| 711.93 | 2.00 | 2.00 |
| 710.95 | 2.51 | 2.51 |
| 696.92 | 2.17 | 2.17 |
| 709.96 | 3.16 | 3.16 |
| 697.90 | 2.60 | 2.60 |
| 663.85 | 2.00 | 2.00 |
| 709.96 | 3.01 | 3.01 |
| 646.86 | 3.36 | 3.36 |
| 711.93 | 2.99 | 2.99 |
| 704.89 | 3.15 | 3.15 |
| 647.85 | 2.76 | 2.76 |