Basic Information
ID: ALA3887391
Type: Binding
Description: GTPase Activity Assay: GTPase assays were performed in 50 mM MES, pH 6.5, 50 mM KCl, 5 mM MgCl2 in the presence of 2 uM FtsZ in the presence of varying concentrations of compound 1. Solutions were incubated at room temperature for 5 min, followed by addition of 0.25 mM GTP. At the end of a 20-min incubation period, enzyme activity was quenched by addition of 50 uL Malachite Green solution and the wells read at A625 on an absorbance plate reader.
Activity Charts
Bioactivity
Activity Types for Assay ALA3887391
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.24 | 4.68 | 4.68 |
| 341.19 | 4.07 | 4.07 |