Basic Information
ID: ALA3887619
Type: Binding
Description: Enzyme Assay: Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroaniline (APpNA, a PRCP chromogenic substrate). The final volume was 100 μL and the time of incubation was 60 min. Negative control had only 1 mM APpNA in HEPES-Carbonated buffer. Generation of free p-nitroaniline from APpNA was determined by monitoring changes in absorbance at 405 nm. Assays were done a minimum of 3 times.
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3887619
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 465.55 | 3.10 | 3.10 |
| 282.47 | 3.78 | 3.78 |
| 504.41 | 4.40 | 4.40 |
| 513.72 | 5.82 | 5.82 |
| 351.54 | 2.99 | 2.99 |
| 435.52 | 3.10 | 3.10 |
| 443.59 | 3.87 | 3.87 |
| 569.83 | 7.38 | 7.38 |
| 507.63 | 2.26 | 2.26 |
| 469.97 | 3.75 | 3.75 |
| 528.45 | 3.90 | 3.90 |
| 365.56 | 3.38 | 3.38 |
| 469.97 | 3.75 | 3.75 |
| 469.97 | 3.75 | 3.75 |
| 492.40 | 4.31 | 4.31 |
| 503.52 | 4.11 | 4.11 |
| 379.59 | 3.77 | 3.77 |
| 365.56 | 3.38 | 3.38 |
| 555.80 | 6.99 | 6.99 |
| 465.55 | 3.10 | 3.10 |
| 479.58 | 3.15 | 3.15 |
| 457.96 | 3.65 | 3.65 |
| 367.58 | 3.67 | 3.67 |
| 484.00 | 3.79 | 3.79 |
| 492.40 | 4.31 | 4.31 |
| 415.53 | 3.09 | 3.09 |
| 268.44 | 3.39 | 3.39 |
| 471.50 | 3.37 | 3.37 |
| 457.96 | 3.65 | 3.65 |
| 457.96 | 3.65 | 3.65 |