Basic Information
ID: ALA3888012
Type: Binding
Description: Inhibition Assay: The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAM9 and ADAM10 according to the same protocol as that described for the TACE enzyme in example 28 but with different substrates (MMP R&D system reference: P126-990 and ADAM R&D system reference: ES003).
Activity Charts
Bioactivity
Activity Types for Assay ALA3888012
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 414.51 | 0.45 | 0.45 |
| 462.55 | 3.21 | 3.21 |
| 398.46 | 1.75 | 1.75 |
| 474.56 | 3.42 | 3.42 |
| 450.54 | 3.07 | 3.07 |