Assay Report Card

Basic Information

ID: ALA3888015

Type: Binding

Description: Inhibition Assay: The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAM9 and ADAM10 according to the same protocol as that described for the TACE enzyme in example 28 but with different substrates (MMP R&D system reference: P126-990 and ADAM R&D system reference: ES003).

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
414.510.450.45
462.553.213.21
398.461.751.75
474.563.423.42
450.543.073.07