Assay Report Card

Basic Information

ID: ALA3888095

Type: Binding

Description: HTS assay: To determine the effectiveness of an individual antagonist, taste tests were performed with a T2R8 specific agonist, the compound of interest and a reference bitter blocker. We have previously described a good hT2R8 antagonist that was proven to have taste effect. It was shown to reduce bitterness of coffee by itself and in combination with a Broad spectrum bitter blocker.

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
381.392.212.21