Basic Information
ID: ALA3888607
Type: Binding
Description: Kinase Inhibition Assay: The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory concentration (IC50) values determined by Millipore UK Ltd; Gemini Crescent; Dundee Technology Park; Dundee DD2 1SW; UK (IC50Profiler). Detailed protocols can be found at: www.millipore.com/drugdiscovery/dd3/assayprotocols.
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3888607
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.38 | 2.76 | 2.76 |
| 396.37 | 2.90 | 2.90 |
| 379.37 | 2.16 | 2.16 |
| 379.37 | 2.16 | 2.16 |
| 379.37 | 2.16 | 2.16 |
| 379.37 | 2.16 | 2.16 |
| 436.46 | 2.62 | 2.62 |
| 435.48 | 2.58 | 2.58 |
| 491.54 | 2.57 | 2.57 |
| 463.53 | 3.19 | 3.19 |
| 518.61 | 2.87 | 2.87 |
| 489.57 | 3.72 | 3.72 |
| 449.51 | 2.80 | 2.80 |
| 422.44 | 2.23 | 2.23 |
| 421.45 | 2.19 | 2.19 |