Basic Information
ID: ALA3888617
Type: Binding
Description: Inhibition Assay: The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described for the TACE enzyme in example 28, but with different substrates (MMP R&D systems, reference: P126-990, and ADAM R&D systems, reference: ES003).
Activity Charts
Bioactivity
Activity Types for Assay ALA3888617
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 414.51 | 0.45 | 0.45 |
| 577.69 | 0.85 | 0.85 |
| 607.71 | 3.23 | 3.23 |
| 527.65 | 1.91 | 1.91 |
| 603.75 | 3.40 | 3.40 |
| 569.68 | 2.07 | 2.07 |
| 619.77 | 1.88 | 1.88 |
| 605.74 | 1.63 | 1.63 |
| 657.72 | 4.11 | 4.11 |