ID: ALA3888734
Type: Binding
Description: Enzymatic Assay: Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a product such as dihydroxyacetone phosphate (DHAP) or glyceraldehyde 3-phosphate (GAP). If the activity is measurably lower in the presence of the candidate compound than in its absence, then the compound has FBA inhibitory activity and is a candidate antibiotic and antiparasitic compound. The compound may also be screened with recombinant or isolated Class I FBA (for example, of human or mammalian origin) to determine cross-inhibition.
Bioactivity
Activity Types for Assay ALA3888734
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
145.16 | 1.94 | 1.94 |
144.18 | 1.82 | 1.82 |
189.17 | 1.64 | 1.64 |
238.27 | 1.31 | 1.31 |