Assay Report Card

Basic Information

ID: ALA3888734

Type: Binding

Description: Enzymatic Assay: Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a product such as dihydroxyacetone phosphate (DHAP) or glyceraldehyde 3-phosphate (GAP). If the activity is measurably lower in the presence of the candidate compound than in its absence, then the compound has FBA inhibitory activity and is a candidate antibiotic and antiparasitic compound. The compound may also be screened with recombinant or isolated Class I FBA (for example, of human or mammalian origin) to determine cross-inhibition.

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
145.161.941.94
144.181.821.82
189.171.641.64
238.271.311.31