Basic Information
ID: ALA3888858
Type: Binding
Description: Inhibition Assay: Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phosphate buffer (pH 6.8), Enzyme: mushroom tyrosinase (T-3824, Sigma), Substrate: L-tyrosine (T-3754, Sigma), Positive control: Kojic acid (KA) (60890, Fluka) (reference inhibitor). Reference Molecules for the Test: Kojic acid: 9 μM
Activity Charts
Bioactivity
Activity Types for Assay ALA3888858
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 142.11 | -0.16 | -0.16 |
| 166.22 | 2.44 | 2.44 |
| 215.25 | 2.64 | 2.64 |
| 217.22 | 1.57 | 1.57 |
| 220.29 | 3.31 | 3.31 |
| 215.25 | 2.64 | 2.64 |
| 214.26 | 3.25 | 3.25 |
| 220.29 | 3.31 | 3.31 |
| 201.22 | 2.08 | 2.08 |
| 221.28 | 2.71 | 2.71 |
| 272.25 | -1.43 | -1.43 |