Basic Information
ID: ALA3991746
Type: Binding
Description: Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry.
Format: BAO_0000220
Organism: Homo sapiens
Cell type: K-562, COLO 205, SK-N-BE(2) and MV-4-11
Subcellular Fraction: Cell lysate
Target: Serine/threonine-protein kinase LATS1(ALA6167)
Document: ALA3991601
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry.: 48
Activity Charts
Bioactivity
Activity Types for Assay ALA3991746
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 398.48 | 3.33 | 3.33 |
| 354.46 | 3.20 | 3.20 |
| 414.41 | 2.41 | 2.41 |
| 475.36 | 4.43 | 4.43 |
| 291.38 | 1.22 | 1.22 |
| 530.46 | 5.19 | 5.19 |
| 446.91 | 4.28 | 4.28 |
| 468.56 | 3.51 | 3.51 |
| 464.83 | 5.55 | 5.55 |
| 557.05 | 5.93 | 5.93 |
| 576.63 | 5.39 | 5.39 |
| 370.38 | 3.52 | 3.52 |
| 441.46 | 1.41 | 1.41 |
| 488.02 | 3.31 | 3.31 |
| 532.41 | 3.86 | 3.86 |
| 529.53 | 6.36 | 6.36 |
| 464.60 | 3.50 | 3.50 |
| 580.09 | 7.09 | 7.09 |
| 400.29 | -1.77 | -1.77 |
| 482.20 | 2.47 | 2.47 |
| 512.90 | 5.19 | 5.19 |
| 425.49 | 1.58 | 1.58 |
| 383.41 | 3.93 | 3.93 |
| 521.67 | 3.56 | 3.56 |
| 382.25 | 2.45 | 2.45 |
| 430.95 | 5.10 | 5.10 |
| 368.47 | 3.07 | 3.07 |
| 383.68 | 5.34 | 5.34 |
| 425.54 | 4.67 | 4.67 |
| 560.68 | 5.86 | 5.86 |
| 431.54 | 3.32 | 3.32 |
| 440.60 | 4.94 | 4.94 |
| 439.47 | 3.47 | 3.47 |
| 450.35 | 5.04 | 5.04 |
| 434.50 | 4.20 | 4.20 |
| 570.65 | 5.91 | 5.91 |
| 383.47 | 3.86 | 3.86 |
| 507.50 | 3.14 | 3.14 |
| 532.57 | 4.46 | 4.46 |
| 485.95 | 4.39 | 4.39 |
| 349.78 | 4.88 | 4.88 |
| 348.77 | 3.01 | 3.01 |
| 618.83 | 4.27 | 4.27 |
| 426.86 | 4.07 | 4.07 |
| 386.48 | 4.64 | 4.64 |
| 457.69 | 3.53 | 3.53 |
| 468.48 | 6.06 | 6.06 |
| 443.45 | 6.06 | 6.06 |
| 465.55 | 2.64 | 2.64 |
| 482.82 | 5.69 | 5.69 |
| 560.65 | 5.03 | 5.03 |
| 372.39 | 1.67 | 1.67 |
| 517.46 | 5.91 | 5.91 |
| 472.59 | 4.47 | 4.47 |
| 362.43 | 2.53 | 2.53 |
| 391.43 | 3.16 | 3.16 |
| 580.47 | 3.09 | 3.09 |
| 396.50 | 2.28 | 2.28 |
| 466.95 | 5.25 | 5.25 |
| 615.40 | 3.94 | 3.94 |
| 369.42 | 3.59 | 3.59 |
| 443.55 | 3.92 | 3.92 |
| 371.43 | 1.10 | 1.10 |
| 431.20 | 1.65 | 1.65 |
| 469.95 | 5.16 | 5.16 |
| 507.01 | 4.67 | 4.67 |
| 503.59 | 6.64 | 6.64 |
| 408.46 | 2.71 | 2.71 |
| 443.50 | 4.42 | 4.42 |
| 369.43 | 3.51 | 3.51 |
| 558.15 | 6.36 | 6.36 |
| 473.94 | 3.76 | 3.76 |
| 392.39 | 3.28 | 3.28 |
| 436.31 | 2.87 | 2.87 |
| 633.70 | 4.75 | 4.75 |
| 406.45 | 3.22 | 3.22 |
| 429.25 | 3.56 | 3.56 |
| 461.23 | 1.83 | 1.83 |
| 534.54 | 4.38 | 4.38 |
| 506.61 | 4.94 | 4.94 |
| 540.02 | 3.91 | 3.91 |
| 552.72 | 2.70 | 2.70 |
| 345.37 | 1.88 | 1.88 |
| 499.62 | 4.51 | 4.51 |
| 457.48 | 3.78 | 3.78 |
| 504.66 | 4.62 | 4.62 |
| 289.72 | 2.75 | 2.75 |
| 491.39 | 5.79 | 5.79 |
| 445.42 | 4.30 | 4.30 |
| 491.35 | 5.38 | 5.38 |
| 334.40 | 3.26 | 3.26 |
| 432.53 | 3.50 | 3.50 |
| 555.56 | 4.78 | 4.78 |
| 444.54 | 3.41 | 3.41 |
| 433.34 | 4.67 | 4.67 |
| 464.57 | 4.17 | 4.17 |
| 619.72 | 6.22 | 6.22 |
| 424.48 | 3.24 | 3.24 |
| 482.01 | 1.37 | 1.37 |