Assay Report Card

Basic Information

ID: ALA3992295

Type: Binding

Description: Inhibition of recombinant full-length N-terminal hexahistidine-tagged c-Myc (353 to 437 residues) bHLH-ZIP domain (unknown origin) expressed in Escherichia coli BL21 DE3 (pLysS)/human hexahistidine-tagged Max p21 expressed in Escherichia coli M15 (pRep4) assessed as disruption of E-Box DNA binding at 25 to 50 nM preincubated for 30 mins with c-Myc followed by Max p21 and E-box element measured after 15 mins by electrophoretic mobility shift assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
249.362.742.74
332.324.544.54