Basic Information
ID: ALA3992696
Type: Binding
Description: Inhibition of 50% inactivated recombinant human Nav1.8 expressed in HEK293 cells coexpressing Nav beta1 subunit at holding potential of -120 mV by manual patch electrophysiology method
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3992696
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.35 | 3.89 | 3.89 |
| 377.37 | 4.19 | 4.19 |
| 328.29 | 2.88 | 2.88 |
| 279.77 | 3.31 | 3.31 |
| 285.27 | 3.17 | 3.17 |
| 315.30 | 2.80 | 2.80 |
| 277.80 | 3.65 | 3.65 |
| 337.31 | 2.94 | 2.94 |
| 314.27 | 1.33 | 1.33 |
| 286.25 | 3.20 | 3.20 |
| 201.27 | 2.27 | 2.27 |
| 321.25 | 3.07 | 3.07 |
| 279.77 | 3.31 | 3.31 |
| 285.27 | 2.87 | 2.87 |
| 285.27 | 3.17 | 3.17 |
| 279.37 | 1.67 | 1.67 |
| 299.30 | 3.21 | 3.21 |
| 377.37 | 4.19 | 4.19 |
| 311.31 | 3.44 | 3.44 |
| 327.31 | 3.35 | 3.35 |
| 231.30 | 2.28 | 2.28 |
| 313.28 | 2.25 | 2.25 |
| 268.36 | 2.86 | 2.86 |
| 285.27 | 2.87 | 2.87 |
| 284.28 | 4.27 | 4.27 |
| 235.72 | 2.92 | 2.92 |
| 303.26 | 3.12 | 3.12 |
| 277.80 | 3.65 | 3.65 |