Basic Information
ID: ALA3993207
Type: Binding
Description: Positive allosteric modulation of human glycine alpha3beta receptor expressed in HEK293T cells assessed as compound concentration required to induce up to 3-fold leftward shift in glycine-induced increase in chloride ion flux after 4 mins by Schild plot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3993207
MEC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 395.44 | 2.49 | 2.49 |
| 405.41 | 1.28 | 1.28 |
| 397.46 | 1.35 | 1.35 |
| 385.45 | 1.40 | 1.40 |
| 387.42 | 1.19 | 1.19 |
| 401.44 | 1.58 | 1.58 |
| 386.43 | 1.80 | 1.80 |
| 401.44 | 1.58 | 1.58 |
| 412.43 | 1.08 | 1.08 |
| 395.44 | 2.49 | 2.49 |
| 383.43 | 2.21 | 2.21 |
| 384.42 | 1.60 | 1.60 |
| 404.42 | 1.94 | 1.94 |
| 401.44 | 1.58 | 1.58 |
| 402.43 | 1.50 | 1.50 |
| 401.44 | 1.58 | 1.58 |
| 385.45 | 1.40 | 1.40 |
| 386.43 | 1.80 | 1.80 |
| 395.84 | 2.25 | 2.25 |
| 383.43 | 1.34 | 1.34 |
| 387.42 | 1.19 | 1.19 |
| 401.44 | 1.58 | 1.58 |
| 401.44 | 1.58 | 1.58 |
| 411.44 | 1.67 | 1.67 |
| 400.46 | 2.19 | 2.19 |
| 383.43 | 2.21 | 2.21 |
| 387.42 | 1.19 | 1.19 |
| 401.44 | 1.58 | 1.58 |
| 387.42 | 1.19 | 1.19 |
| 401.44 | 1.37 | 1.37 |
| 383.43 | 1.11 | 1.11 |
| 383.43 | 2.21 | 2.21 |
| 400.49 | 2.07 | 2.07 |
| 387.42 | 1.19 | 1.19 |
| 401.44 | 1.58 | 1.58 |