Assay Report Card

Basic Information

ID: ALA3993362

Type: Functional

Description: Antinociceptive activity in TREK1 deficient C57Bl/6J mouse assessed as increase in thermal-stimulus induced paw withdrawal latency at 60 mg/kg, sc measured after 45 mins by hot plate method relative to control

Organism: Mus musculus

Strain: C57Bl/6J

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
285.341.201.20
163.131.271.27
238.252.832.83
251.293.313.31
287.323.713.71