Assay Report Card

Basic Information

ID: ALA3993636

Type: ADME

Description: Effect on normal pain sensitivity in complete Freund's adjuvant-induced Sprague-Dawley rat rheumatoid arthritis model assessed as change in contralateral paw withdrawal threshold at 10 mg/kg, po administered once on day 14 post complete Freund's adjuvant challenge measured after 15 to 75 mins by analgesimetry

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
431.464.904.90
543.625.585.58
544.995.145.14
441.484.324.32
544.995.145.14
442.473.513.51
431.464.904.90
483.355.585.58
393.484.294.29