Basic Information
ID: ALA3993755
Type: Binding
Description: Inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation at 100 uM using 3-phosphoglycerate as substrate preincubated measured for 7 mins in presence of NAD+ by spectrophotometric method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3993755
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 108.10 | 0.25 | 0.25 |
| 322.41 | 3.67 | 3.67 |
| 158.16 | 1.62 | 1.62 |
| 207.62 | 1.77 | 1.77 |
| 154.24 | 1.60 | 1.60 |
| 256.33 | 0.29 | 0.29 |
| 234.37 | 3.31 | 3.31 |
| 307.36 | 2.22 | 2.22 |
| 276.19 | 3.00 | 3.00 |
| 276.68 | 3.50 | 3.50 |
| 332.36 | 4.11 | 4.11 |
| 163.22 | 1.35 | 1.35 |
| 447.45 | 5.24 | 5.24 |
| 251.42 | 3.99 | 3.99 |
| 272.26 | 2.25 | 2.25 |