Basic Information
ID: ALA3993756
Type: Binding
Description: Inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation using 3-phosphoglycerate as substrate in presence of NAD+ by resorufin fluorescence based PSAT1/diaphorase/PSPH coupled enzyme assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3993756
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 276.19 | 3.00 | 3.00 |
| 253.30 | 1.67 | 1.67 |
| 276.68 | 3.50 | 3.50 |
| 361.20 | 2.13 | 2.13 |
| 269.75 | 2.18 | 2.18 |
| 253.30 | 1.67 | 1.67 |
| 280.30 | 1.44 | 1.44 |
| 361.20 | 2.13 | 2.13 |
| 314.20 | 2.29 | 2.29 |
| 280.30 | 1.44 | 1.44 |
| 235.31 | 1.53 | 1.53 |
| 314.20 | 2.29 | 2.29 |
| 269.75 | 2.18 | 2.18 |
| 253.30 | 1.67 | 1.67 |
| 280.30 | 1.44 | 1.44 |
| 361.20 | 2.13 | 2.13 |
| 269.75 | 2.18 | 2.18 |
| 311.41 | 3.20 | 3.20 |
| 314.20 | 2.29 | 2.29 |