Basic Information
ID: ALA3993763
Type: Binding
Description: Ratio of IC50 for inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium to IC50 for inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3993763
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 276.19 | 3.00 | 3.00 |
| 253.30 | 1.67 | 1.67 |
| 276.68 | 3.50 | 3.50 |
| 361.20 | 2.13 | 2.13 |
| 253.30 | 1.67 | 1.67 |
| 280.30 | 1.44 | 1.44 |
| 361.20 | 2.13 | 2.13 |
| 314.20 | 2.29 | 2.29 |
| 280.30 | 1.44 | 1.44 |
| 235.31 | 1.53 | 1.53 |
| 314.20 | 2.29 | 2.29 |
| 253.30 | 1.67 | 1.67 |
| 280.30 | 1.44 | 1.44 |
| 361.20 | 2.13 | 2.13 |
| 269.75 | 2.18 | 2.18 |
| 311.41 | 3.20 | 3.20 |
| 314.20 | 2.29 | 2.29 |