ID: ALA3993766
Type: Binding
Description: Non-competitive inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation preincubated for 30 mins followed by constant concentration of 3-phosphoglycerate substrate addition in presence of varying levels of NAD+ by resorufin fluorescence based PSAT1/diaphorase/PSPH coupled enzyme assay
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA3993766
Ki
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
235.31 | 1.53 | 1.53 |