Assay Report Card

Basic Information

ID: ALA3993766

Type: Binding

Description: Non-competitive inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation preincubated for 30 mins followed by constant concentration of 3-phosphoglycerate substrate addition in presence of varying levels of NAD+ by resorufin fluorescence based PSAT1/diaphorase/PSPH coupled enzyme assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
235.311.531.53