Basic Information
ID: ALA3993767
Type: Binding
Description: Covalent inhibition of human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli at 160 uM using 3-phosphoglycerate as substrate preincubated for 45 mins followed by 10-fold compound dilution in presence of NAD+ by resorufin fluorescence based PSAT1/diaphorase/PSPH coupled enzyme assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3993767
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 235.31 | 1.53 | 1.53 |