Basic Information
ID: ALA3993769
Type: Binding
Description: Inverse agonist at mouse brain CB1R expressed in CHOK1 cell membranes assessed as inhibition of CP55940-stimulated [35S]GTP-gammaS binding measured after 60 mins by scintillation spectrometry
Format: BAO_0000219
Organism: Mus musculus
Target: Cannabinoid CB1 receptor(ALA3037)
Document: ALA3992534
Inverse agonist at mouse brain CB1R expressed in CHOK1 cell membranes assessed as inhibition of CP55940-stimulated [35S]GTP-gammaS binding measured after 60 mins by scintillation spectrometry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3993769
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 463.80 | 5.94 | 5.94 |
| 487.41 | 4.76 | 4.76 |
| 612.49 | 6.23 | 6.23 |
| 636.63 | 6.83 | 6.83 |
| 536.10 | 5.56 | 5.56 |
| 606.54 | 5.98 | 5.98 |
| 634.63 | 7.12 | 7.12 |
| 596.54 | 5.03 | 5.03 |
| 574.56 | 6.00 | 6.00 |
| 577.50 | 5.34 | 5.34 |
| 497.98 | 4.40 | 4.40 |
| 514.44 | 4.92 | 4.92 |
| 637.96 | 5.17 | 5.17 |
| 563.99 | 5.16 | 5.16 |
| 594.50 | 6.09 | 6.09 |
| 530.05 | 5.42 | 5.42 |
| 494.02 | 4.57 | 4.57 |
| 582.54 | 6.01 | 6.01 |
| 655.41 | 6.71 | 6.71 |
| 594.50 | 6.09 | 6.09 |
| 546.51 | 5.22 | 5.22 |
| 540.48 | 5.31 | 5.31 |
| 547.99 | 5.28 | 5.28 |
| 510.02 | 4.27 | 4.27 |
| 577.50 | 5.34 | 5.34 |
| 576.51 | 5.95 | 5.95 |
| 650.66 | 7.22 | 7.22 |
| 479.99 | 4.27 | 4.27 |
| 542.49 | 5.56 | 5.56 |
| 558.89 | 5.03 | 5.03 |
| 562.12 | 5.72 | 5.72 |
| 522.07 | 5.39 | 5.39 |
| 610.95 | 6.60 | 6.60 |
| 622.60 | 6.79 | 6.79 |
| 655.41 | 6.71 | 6.71 |
| 606.54 | 5.96 | 5.96 |
| 580.06 | 5.58 | 5.58 |
| 556.52 | 5.95 | 5.95 |
| 605.89 | 4.87 | 4.87 |
| 560.53 | 5.61 | 5.61 |