Basic Information
ID: ALA3993868
Type: Binding
Description: Binding affinity to human IgG1-fused Siglec-7-Fc assessed as inhibition of Siglec-7-Fc binding to RBC preincubated for 10 mins followed by RBC addition measured after 20 mins by FACS analysis relative to sodium (4S,5R,6R)-5-acetamido-4-hydroxy-2-methoxy-6-((1R,2R)-1,2,3 trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylate
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3993868
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 669.69 | -0.27 | -0.27 |
| 804.81 | 0.94 | 0.94 |
| 462.43 | -1.85 | -1.85 |
| 771.74 | -2.20 | -2.20 |
| 633.63 | 0.31 | 0.31 |
| 731.76 | 1.15 | 1.15 |
| 738.73 | 0.93 | 0.93 |
| 697.74 | 0.51 | 0.51 |
| 807.86 | 2.82 | 2.82 |
| 687.64 | -0.41 | -0.41 |
| 723.66 | 0.62 | 0.62 |
| 608.65 | 1.11 | 1.11 |
| 512.49 | -0.70 | -0.70 |
| 576.58 | 1.20 | 1.20 |
| 538.53 | -0.18 | -0.18 |
| 685.60 | -0.62 | -0.62 |
| 415.33 | -4.61 | -4.61 |
| 745.79 | 1.30 | 1.30 |
| 463.42 | -1.39 | -1.39 |
| 448.40 | -1.78 | -1.78 |
| 520.56 | -0.49 | -0.49 |
| 709.73 | 1.53 | 1.53 |
| 693.64 | -0.43 | -0.43 |
| 824.89 | 2.37 | 2.37 |
| 681.72 | 1.97 | 1.97 |
| 633.68 | 1.18 | 1.18 |
| 524.50 | -0.11 | -0.11 |
| 711.77 | 0.90 | 0.90 |
| 592.58 | 0.17 | 0.17 |
| 683.72 | 0.12 | 0.12 |
| 670.68 | -1.03 | -1.03 |
| 591.60 | 0.13 | 0.13 |
| 512.49 | -0.70 | -0.70 |
| 468.48 | -1.12 | -1.12 |
| 662.63 | -1.22 | -1.22 |
| 491.43 | -2.46 | -2.46 |