Assay Report Card

Basic Information

ID: ALA3994157

Type: Functional

Description: Cell cycle arrest in human NCI-H727 cells harboring p53 mutant assessed as accumulation at S phase at 25 uM measured after 48 hrs by Hoechst/BrdU staining based fluorescence assay (Rvb = 40.3%)

Organism: Homo sapiens

Cell type: NCI-H727

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
354.463.203.20
298.343.613.61
328.363.623.62
332.784.264.26
284.313.313.31
314.343.313.31
314.343.313.31
348.362.982.98
302.303.443.44
316.333.753.75
377.234.374.37
344.434.334.33
330.404.034.03