Basic Information
ID: ALA3994269
Type: Binding
Description: Inhibition of GFP-fused rat Cav1.2 expressed in human tsA-201 cells co-expressing Cavbeta1b/Cavalpha2delta1 assessed as tonic block at 10 uM at holding potential of -90 mV by whole cell patch clamp method relative to control
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA3994269
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 531.55 | 1.90 | 1.90 |
| 493.52 | 3.43 | 3.43 |
| 455.47 | 3.04 | 3.04 |
| 497.48 | 3.18 | 3.18 |
| 508.56 | 4.34 | 4.34 |
| 583.65 | 5.21 | 5.21 |
| 597.67 | 5.60 | 5.60 |
| 517.50 | 2.16 | 2.16 |
| 616.70 | 4.17 | 4.17 |
| 644.69 | 5.18 | 5.18 |
| 479.49 | 3.04 | 3.04 |
| 520.50 | 2.36 | 2.36 |
| 505.53 | 3.70 | 3.70 |
| 569.62 | 4.82 | 4.82 |
| 503.51 | 2.33 | 2.33 |
| 526.58 | 2.91 | 2.91 |
| 492.49 | 3.87 | 3.87 |
| 511.51 | 3.57 | 3.57 |
| 566.60 | 3.06 | 3.06 |