Basic Information
ID: ALA3994508
Type: Binding
Description: Irreversible inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by compound washout and doxycyclin addition to induce Bim protein expression measured after 24 hrs by Cell Titer-Glo assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3994508
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 308.31 | 2.63 | 2.63 |
| 302.28 | 2.57 | 2.57 |
| 443.83 | 3.43 | 3.43 |
| 443.83 | 3.43 | 3.43 |
| 439.42 | 2.78 | 2.78 |
| 394.40 | 2.95 | 2.95 |
| 674.74 | 5.03 | 5.03 |
| 439.42 | 2.78 | 2.78 |
| 409.39 | 2.78 | 2.78 |
| 443.83 | 3.43 | 3.43 |
| 469.44 | 2.79 | 2.79 |
| 467.47 | 3.56 | 3.56 |