Basic Information
ID: ALA3994743
Type: Binding
Description: Inhibition of Escherichia coli FabH expressed in Escherichia coli DH10B using holo-ACP/acetyl-CoA as substrate assessed as incorporation of [3H] signal in final product preincubated with holo-ACP for 1 hr followed by acetyl-CoA addition measured after 25 mins by liquid scintillation counting method
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA3994743
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 483.52 | -7.33 | -7.33 |
| 364.32 | 3.63 | 3.63 |
| 357.32 | 2.23 | 2.23 |
| 375.77 | 3.17 | 3.17 |
| 326.35 | 2.62 | 2.62 |
| 357.32 | 2.23 | 2.23 |
| 422.22 | 3.22 | 3.22 |
| 359.31 | 2.66 | 2.66 |
| 355.39 | 2.38 | 2.38 |
| 372.38 | 2.33 | 2.33 |
| 365.22 | 3.92 | 3.92 |
| 346.39 | 3.77 | 3.77 |
| 312.32 | 2.32 | 2.32 |
| 328.32 | 2.02 | 2.02 |
| 359.31 | 2.66 | 2.66 |
| 356.38 | 2.63 | 2.63 |
| 341.32 | 2.52 | 2.52 |
| 346.77 | 2.97 | 2.97 |
| 381.21 | 3.62 | 3.62 |
| 314.32 | 2.75 | 2.75 |
| 375.77 | 3.17 | 3.17 |
| 259.35 | 3.60 | 3.60 |
| 339.40 | 2.68 | 2.68 |
| 386.40 | 2.64 | 2.64 |
| 348.76 | 3.40 | 3.40 |
| 346.39 | 3.77 | 3.77 |
| 372.42 | 4.28 | 4.28 |