Basic Information
ID: ALA3994901
Type: Binding
Description: Inhibition of HMG-CoA reductase in pig liver microsomes using HMG-CoA as substrate preincubated for 5 mins followed by NADPH addition measured after 15 mins by colorimetric method
Organism: Sus scrofa
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3994901
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 558.65 | 6.31 | 6.31 |
| 360.45 | 4.84 | 4.84 |
| 344.45 | 5.12 | 5.12 |
| 358.43 | 4.76 | 4.76 |
| 356.42 | 4.27 | 4.27 |
| 360.45 | 3.77 | 3.77 |
| 386.44 | 4.03 | 4.03 |
| 342.44 | 5.10 | 5.10 |
| 344.45 | 5.12 | 5.12 |