Basic Information
ID: ALA3994954
Type: Binding
Description: Inhibition of recombinant human N-terminal GST-tagged RAF1 (306-end residues) expressed in baculovirus infected Sf21 cells in presence of [gamma33P]ATP by HTRF assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Serine/threonine-protein kinase RAF(ALA1906)
Document: ALA3994581
Inhibition of recombinant human N-terminal GST-tagged RAF1 (306-end residues) expressed in baculovirus infected Sf21 cells in presence of [gamma33P]ATP by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3994954
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 432.25 | 4.86 | 4.86 |
| 396.45 | 4.55 | 4.55 |
| 369.43 | 4.26 | 4.26 |
| 456.48 | 4.17 | 4.17 |
| 421.35 | 5.11 | 5.11 |
| 365.46 | 4.43 | 4.43 |
| 418.28 | 5.57 | 5.57 |
| 406.47 | 4.87 | 4.87 |
| 367.38 | 4.40 | 4.40 |
| 433.46 | 5.45 | 5.45 |
| 379.42 | 4.27 | 4.27 |
| 313.36 | 2.90 | 2.90 |
| 444.36 | 5.19 | 5.19 |
| 452.52 | 4.34 | 4.34 |
| 422.25 | 5.40 | 5.40 |
| 383.38 | 4.10 | 4.10 |
| 428.29 | 5.03 | 5.03 |
| 467.90 | 6.10 | 6.10 |
| 437.42 | 5.28 | 5.28 |
| 452.52 | 4.34 | 4.34 |
| 451.84 | 5.94 | 5.94 |
| 454.51 | 5.33 | 5.33 |
| 471.87 | 5.93 | 5.93 |
| 383.84 | 4.92 | 4.92 |
| 455.80 | 5.77 | 5.77 |
| 450.54 | 5.50 | 5.50 |
| 400.41 | 4.38 | 4.38 |
| 356.41 | 3.72 | 3.72 |
| 365.46 | 4.43 | 4.43 |
| 417.39 | 5.28 | 5.28 |