Basic Information
ID: ALA3995154
Type: Binding
Description: Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence of NADH by RP-HPLC method
Format: BAO_0000019
Organism: Homo sapiens
Target: Estradiol 17-beta-dehydrogenase 1(ALA3181)
Document: ALA3994586
Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence of NADH by RP-HPLC method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3995154
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 506.96 | 4.65 | 4.65 |
| 366.77 | 4.99 | 4.99 |
| 520.99 | 4.96 | 4.96 |
| 380.80 | 5.29 | 5.29 |
| 366.77 | 4.99 | 4.99 |
| 380.80 | 5.30 | 5.30 |
| 395.41 | 3.28 | 3.28 |
| 332.33 | 4.34 | 4.34 |
| 334.32 | 4.77 | 4.77 |
| 346.35 | 4.64 | 4.64 |
| 399.42 | 5.29 | 5.29 |
| 447.85 | 4.63 | 4.63 |
| 374.41 | 5.26 | 5.26 |
| 415.24 | 5.95 | 5.95 |
| 352.31 | 4.91 | 4.91 |
| 461.88 | 4.93 | 4.93 |
| 365.24 | 5.36 | 5.36 |
| 316.33 | 4.63 | 4.63 |
| 316.33 | 4.63 | 4.63 |
| 357.34 | 4.21 | 4.21 |
| 379.26 | 5.67 | 5.67 |
| 478.95 | 4.70 | 4.70 |
| 317.32 | 4.02 | 4.02 |
| 401.22 | 5.64 | 5.64 |
| 370.30 | 5.05 | 5.05 |
| 395.41 | 3.28 | 3.28 |
| 495.53 | 3.66 | 3.66 |
| 350.77 | 5.28 | 5.28 |
| 360.38 | 4.95 | 4.95 |
| 317.32 | 4.02 | 4.02 |
| 394.83 | 5.60 | 5.60 |
| 330.36 | 4.94 | 4.94 |