Basic Information
ID: ALA3995686
Type: Binding
Description: Inhibition of topoisomerase-1/topoisomerase-2 in human HCT15 cell nuclear extract at 50 uM preincubated for 24 hrs followed by supercoiled pBR322 DNA addition measured after 20 mins by ethidium bromide staining based agarose gel electrophoresis method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3995686
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 588.56 | 1.34 | 1.34 |
| 371.82 | 6.67 | 6.67 |