Basic Information
ID: ALA3996878
Type: Functional
Description: Negative allosteric modulation of rat N-terminal HA-tagged mGlu5 receptor expressed in HEK293 cells co-expressing N-terminal HA-tagged EAAC1 assessed as inhibition of quisqualate-induced inositol phosphate accumulation after 30 mins by HTRF assay
Format: BAO_0000219
Organism: Rattus norvegicus
Target: Metabotropic glutamate receptor 5(ALA2564)
Document: ALA3994627
Negative allosteric modulation of rat N-terminal HA-tagged mGlu5 receptor expressed in HEK293 cells co-expressing N-terminal HA-tagged EAAC1 assessed as inhibition of quisqualate-induced inositol phosphate accumulation after 30 mins by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3996878
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.69 | 1.29 | 1.29 |
| 288.31 | 5.31 | 5.31 |
| 280.33 | 3.28 | 3.28 |
| 284.32 | 4.29 | 4.29 |
| 288.31 | 5.31 | 5.31 |
| 280.33 | 3.28 | 3.28 |
| 284.32 | 4.29 | 4.29 |