Basic Information
ID: ALA3997541
Type: Binding
Description: Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated for 2 hrs followed by substrate addition measured every 2 minutes for 50 minutes by Amplex red dye based fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3997541
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 125.15 | 1.28 | 1.28 |
| 107.16 | 1.15 | 1.15 |
| 121.18 | 1.19 | 1.19 |
| 165.19 | 0.93 | 0.93 |
| 122.17 | 0.73 | 0.73 |
| 149.20 | 0.43 | 0.43 |
| 108.14 | 0.54 | 0.54 |
| 152.15 | 1.05 | 1.05 |
| 70.09 | -0.14 | -0.14 |
| 165.19 | 0.93 | 0.93 |
| 200.24 | 2.33 | 2.33 |
| 266.39 | ||
| 158.20 | 1.69 | 1.69 |
| 138.17 | 0.55 | 0.55 |
| 132.17 | 1.02 | 1.02 |
| 142.59 | 1.19 | 1.19 |
| 185.23 | 1.60 | 1.60 |
| 190.27 | 2.27 | 2.27 |
| 126.13 | 0.68 | 0.68 |
| 136.20 | 1.19 | 1.19 |
| 253.23 | 2.62 | 2.62 |
| 122.17 | 0.58 | 0.58 |
| 176.14 | 1.56 | 1.56 |
| 149.20 | 0.43 | 0.43 |
| 146.19 | 1.28 | 1.28 |
| 174.21 | 0.73 | 0.73 |
| 126.13 | 0.68 | 0.68 |