Basic Information
ID: ALA3997707
Type: Binding
Description: Antagonist activity at rat TRPV4 expressed in HEK293 cells assessed as inhibition of GSK634775A-induced calcium influx preincubated for 10 mins followed by GSK634775A addition by Fura-4 dye based FLIPR assay
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA3997707
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 600.73 | 7.86 | 7.86 |
| 567.18 | 7.50 | 7.50 |
| 602.70 | 6.71 | 6.71 |
| 698.75 | 8.80 | 8.80 |
| 614.76 | 8.25 | 8.25 |
| 560.66 | 6.94 | 6.94 |
| 586.70 | 7.30 | 7.30 |
| 599.74 | 9.20 | 9.20 |
| 691.64 | 8.55 | 8.55 |
| 562.76 | 6.85 | 6.85 |
| 733.60 | 9.17 | 9.17 |
| 614.76 | 8.04 | 8.04 |
| 562.76 | 6.85 | 6.85 |
| 567.18 | 7.50 | 7.50 |
| 532.73 | 6.84 | 6.84 |
| 600.73 | 7.86 | 7.86 |
| 654.70 | 8.40 | 8.40 |
| 517.60 | 7.40 | 7.40 |
| 532.73 | 6.84 | 6.84 |
| 601.72 | 6.28 | 6.28 |
| 642.77 | 7.80 | 7.80 |
| 684.73 | 8.41 | 8.41 |
| 628.78 | 8.50 | 8.50 |
| 612.74 | 7.79 | 7.79 |
| 600.73 | 7.86 | 7.86 |
| 546.76 | 7.15 | 7.15 |
| 733.60 | 9.17 | 9.17 |
| 656.79 | 8.19 | 8.19 |
| 546.76 | 7.15 | 7.15 |
| 654.70 | 8.40 | 8.40 |