Basic Information
ID: ALA3998487
Type: Binding
Description: Antagonist activity at recombinant human glycine receptor alpha 1 expressed in human tsA201 cells assessed as inhibition of glycine-induced receptor activation after 30 mins by FLIPR membrane potential blue assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Glycine receptor subunit alpha-1(ALA5845)
Document: ALA3997776
Antagonist activity at recombinant human glycine receptor alpha 1 expressed in human tsA201 cells assessed as inhibition of glycine-induced receptor activation after 30 mins by FLIPR membrane potential blue assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3998487
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 334.42 | 2.09 | 2.09 |
| 419.53 | 2.73 | 2.73 |
| 349.43 | 1.67 | 1.67 |
| 477.56 | 2.42 | 2.42 |
| 467.57 | 3.32 | 3.32 |
| 405.50 | 2.49 | 2.49 |
| 457.41 | 3.02 | 3.02 |
| 403.48 | 2.26 | 2.26 |
| 348.40 | 1.62 | 1.62 |
| 453.54 | 3.28 | 3.28 |
| 433.55 | 3.27 | 3.27 |
| 363.42 | 1.53 | 1.53 |
| 419.53 | 2.88 | 2.88 |
| 435.48 | 1.25 | 1.25 |
| 405.50 | 2.44 | 2.44 |
| 377.44 | 1.70 | 1.70 |
| 401.47 | 1.71 | 1.71 |